| 词条 | Simon focus |
| 释义 |
A Simon focus is a tuberculosis (TB) nodule that can form in the apex of the lung when a primary TB infection elsewhere in the body spreads to the lung apex via the bloodstream.[1] Simon focus nodules are often calcified.[1] The initial lesion is usually a small focus of consolidation, less than 2cm in diameter and located within 1 to 2 cm of the apical pleura.[2] In adolescence, Simon foci may become reactivated and develop into Assmann foci.[3] Such foci are sharply circumscribed, firm, gray-white to yellow areas that have a variable amount of central caseation and peripheral fibrosis. References1. ^1 {{cite journal|last=Leung|first=AN|title=Pulmonary tuberculosis: the essentials.|journal=Radiology|date=February 1999|volume=210|issue=2|pages=307–22|pmid=10207408|doi=10.1148/radiology.210.2.r99ja34307}} {{Infectious-disease-stub}}2. ^{{cite book|title=Robbins Basic Pathology (8th edition)|publisher=Elsevier|year=2007|isbn=978-1-4160-2973-1}} 3. ^{{cite web|url=http://medicine.academic.ru/124900/Assmann_focus|title=Assmann focus|publisher=Medicine.academic.ru|accessdate=4 March 2015}} 2 : Tuberculosis|Lung anatomy |
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