Sirianni is a surname. Notable people with the surname include:

• Carmel Sirianni (1922–1991), American politician
• Joseph Sirianni (born 1975), Australian tennis player
• Mike Sirianni (born 1972), American football player and coach
• Nick Sirianni (born 1981), American football coach
• Patrick Sirianni (born 1981), Canadian Musician and Novelist
• Robert Sirianni (born 1983), Canadian-born Italian ice hockey player

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