词条 | Small molecule drug conjugate |
释义 |
The most advanced SMDC is vintafolide, a derivative of the anti-mitotic chemotherapy drug vinblastine which is chemically linked to folic acid.[2] SMDCs are currently being developed by Endocyte for treating cancer, inflammatory diseases and kidney disease, as well as a companion imaging agent that is created by replacing the potent drug with an imaging agent.[3][4] References1. ^{{Cite web | url=http://www.radiologytoday.net/archive/rt0213p12.shtml | title=Ultrasound First — AIUM Initiative Points Out the Diagnostic Benefits and Cost Savings of Using Ultrasound as the Primary Imaging Modality in Many Cases}} 2. ^{{Cite web | url=http://www.radiologytoday.net/archive/rt0213p12.shtml | title=Ultrasound First — AIUM Initiative Points Out the Diagnostic Benefits and Cost Savings of Using Ultrasound as the Primary Imaging Modality in Many Cases}} 3. ^http://www.ddn-news.com/index.php?pg=77&articleid=6278 4. ^{{Cite web | url=http://www.radiologytoday.net/archive/rt0213p12.shtml | title=Ultrasound First — AIUM Initiative Points Out the Diagnostic Benefits and Cost Savings of Using Ultrasound as the Primary Imaging Modality in Many Cases}} 1 : Drug delivery devices |
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