| 词条 | SoRI-9804 |
| 释义 |
| ImageFile = SoRI-9804.svg | ImageSize = 150px | ImageAlt = | IUPACName = N-Benzhydryl-2-phenylquinazolin-4-amine | OtherNames = Benzhydryl-(2-phenyl-quinazolin-4-yl)-amine; 4-((Diphenylmethyl)amino)-2-phenylquinazoline |Section1={{Chembox Identifiers | CASNo = | PubChem = 9930153 | InChI=1S/C27H21N3/c1-4-12-20(13-5-1)25(21-14-6-2-7-15-21)29-27-23-18-10-11-19-24(23)28-26(30-27)22-16-8-3-9-17-22/h1-19,25H,(H,28,29,30) | InChIKey= LJIQXEUCYVPWRY-UHFFFAOYSA-N | SMILES = C1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=N2)NC(C4=CC=CC=C4)C5=CC=CC=C5}} |Section2={{Chembox Properties | C=27 | H=21 | N=3 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}SoRI-9804 is a positive allosteric modulator of dopamine transporters. Unlike others in its series & traditional DRI ligands, it inhibits the release of dopamine in addition to inhibiting the reuptake of released dopamine back into the transporter.[1] See also
References1. ^{{cite journal | pmid= 19244097 | title = Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release | doi=10.1124/jpet.108.149088 | pmc=2672863 | volume=329 | issue=2 |date=May 2009 | pages=718–28}} {{Dopaminergics}}{{organic-compound-stub}} 1 : Quinazolines |
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