| 词条 | Spike (database) |
| 释义 |
|title = SPIKE |logo = |description = highly curated human signaling pathways. |scope = |organism =Homo sapiens |center =Sackler School of Medicine, Tel Aviv University, Israel. |laboratory = Department of Human Molecular Genetics and Biochemistry, |author = Arnon Paz |citation = Paz & al. (2011)[1] |released = 2010 |standard = |format = |url = http://www.cs.tau.ac.il/~spike/ |download =http://www.cs.tau.ac.il/~spike/formats.html |webservice = |sql = |sparql = |webapp = |standalone = |license = |versioning = |frequency = |curation = |bookmark = |version= }}SPIKE (Signaling Pathways Integrated Knowledge Engine) is a database of highly curated interactions for particular human pathways.[1] SPIKE was developed by Ron Shamir's computational biology group in cooperation with the group of Yosef Shiloh, an Israel Prize recipient for his research in systems biology, and the group of Karen B. Avraham, a leading researcher of human deafness, all from Tel-Aviv University. See also
References1. ^1 {{cite journal |last=Paz|first=Arnon |author2=Brownstein Zippora |author3=Ber Yaara |author4=Bialik Shani |author5=David Eyal |author6=Sagir Dorit |author7=Ulitsky Igor |author8=Elkon Ran |author9=Kimchi Adi |author10=Avraham Karen B |author11=Shiloh Yosef |author12=Shamir Ron |date=Jan 2011|title=SPIKE: a database of highly curated human signaling pathways|journal = Nucleic Acids Res.|volume=39|issue=Database issue|pages=D793-9|publisher= |location = England| issn = | pmid = 21097778|doi = 10.1093/nar/gkq1167| bibcode = | oclc =| id = | url = | pmc =3014840 | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }} External links
4 : Biological databases|Cell signaling|Signal transduction|Systems biology |
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