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词条 Stage specific embryonic antigen 3
释义

  1. References

Stage-specific embryonic antigen 3 (SSEA-3) is a glycosphingolipid, specifically, an oligosaccharide composed of five carbohydrate units connected to a sphingolipid. Sphingolipids were originally discovered in 1884 by Johann Ludwig Wilhelm Thudichum who named them after the Sphinx of Greek mythology in reference to the unresolved riddle of their function.[1] It is now known that sphingolipids function as key players in cell signaling [2] and the SSEA-3 molecule as a whole plays a key role in identifying many types of mammalian cells with pluripotent and stem cell-like characteristics.[3][4]

References

1. ^{{Cite book | last = Thudichum| first = John Louis William| title = A Treatise on the Chemical Constitution of Brain| publisher= Bailliere, Tindall, and Cox| location=London| year = 1884| oclc = 253038666}}
2. ^{{Cite journal| last = Futerman | first = AH| last2 = Hannun | first2 = YA| title = The complex life of simple sphingolipids| journal = EMBO Reports |volume = 5 |issue=8 |pages=777–782| year = 2004| pmid = 15289826 | pmc=1299119 | doi=10.1038/sj.embor.7400208}}
3. ^{{Cite journal|last=Kuroda|first=Yasumasa|last2=Kitada|first2=Masaaki|last3=Wakao|first3=Shohei|last4=Nishikawa|first4=Kouki|last5=Tanimura|first5=Yukihiro|last6=Makinoshima|first6=Hideki|last7=Goda|first7=Makoto|last8=Akashi|first8=Hideo|last9=Inutsuka|first9=Ayumu|date=2010-05-11|title=Unique multipotent cells in adult human mesenchymal cell populations|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=107|issue=19|pages=8639–8643|doi=10.1073/pnas.0911647107|issn=1091-6490|pmc=2889306|pmid=20421459}}
4. ^{{Cite journal| last = Byrne| first = James| title = A mini-review on stage-specific embryonic antigen 3 (SSEA-3)| journal = eJournal of Cellular Biotechnology | volume = 1:eP3| date = 2011-07-01| url = http://biotechnologyfoundation.org/discussion-forum?mingleforumaction=viewtopic&t=9}}

1 : Glycolipids

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