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词条 Steven E. Brenner
释义

  1. Education

  2. Career and research

     Awards and honors 

  3. References

{{Infobox scientist
| name = Steven Brenner
| birth_name = Steven Elliot Brenner
| image = File:Steven E. Brenner ISMB 2015.jpg
| image_size =
| alt =
| caption = Steven E. Brenner speaking at the ISMB conference in 2015.
| birth_date =
| birth_place =
| death_date =
| death_place =
| residence =
| citizenship =
| nationality =
| fields =
| workplaces = {{Plainlist|
  • University of California, Berkeley
  • Laboratory of Molecular Biology, Cambridge}}

| alma_mater = {{Plainlist|
  • Harvard University (BS)
  • University of Cambridge (PhD)}}

| doctoral_advisor = Cyrus Chothia
| thesis_title = Molecular propinquity: evolutionary and structural relationships of proteins
| thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596888
| thesis_year = 1996
| academic_advisors =
| doctoral_students =
| notable_students =
| known_for = Structural Classification of Proteins
| influences =
| influenced =
| awards = Overton Prize (2010)[1]
| signature =
| signature_alt =
| footnotes =
| spouse =
| website = {{URL|http://compbio.berkeley.edu}}
}}

Steven Elliot Brenner is a professor at the Department of Plant and Microbial Biology at the University of California Berkeley, Adjunct Professor at the Department of Bioengineering and Therapeutic Sciences at the University of California, and San Francisco

Faculty Scientist, Physical Biosciences at the Lawrence Berkeley National Laboratory.[2][3][4]

Education

Brenner gained his Bachelor of Arts in 1992 from Harvard University and Doctor of Philosophy in 1997 from the University of Cambridge for research supervised by Cyrus Chothia.[5][6] He was one of the creators of the Structural Classification of Proteins (SCOP) database[7] while working at the Laboratory of Molecular Biology (LMB) in Cambridge, UK.

Career and research

{{As of|2017}} research in Brenner's laboratory investigates:
  • Individual genome interpretation[2]
  • The regulation of gene expression by alternative splicing and nonsense-mediated decay of messenger RNA[2]
  • Protein function prediction using Bayesian phylogenomics[2]

Awards and honors

In 2010 he was awarded the Overton Prize from the International Society for Computational Biology.[1][8]

References

1. ^{{Cite journal | last1 = McKay | first1 = B. M. | last2 = Sansom | first2 = C. | doi = 10.1371/journal.pcbi.1000831 | title = 2010 ISCB Overton Prize Awarded to Steven E. Brenner | journal = PLOS Computational Biology | volume = 6 | issue = 6 | pages = e1000831 | year = 2010 | pmid = 20585610| pmc =2891695 }} {{open access}}
2. ^{{cite web|url=http://compbio.berkeley.edu|title=Brenner Laboratory: Computational Genomics Research Group|website=compbio.berkeley.edu|first=Steven|last=Brenner|year=2017}}
3. ^{{Cite journal | last1 = Brenner | first1 = Steven E.| authorlink1 = Steven E. Brenner | title = Be prepared for the big genome leak: It is only a matter of time until idealism sees the release of confidential genetic data on study participants| doi = 10.1038/498139a | journal = Nature | volume = 498 | issue = 7453 | pages = 139 | year = 2013 | pmid = 23765454| pmc = }}
4. ^{{Cite journal | last1 = Stajich | first1 = J. E. | last2 = Block | first2 = D. | last3 = Boulez | first3 = K. | last4 = Brenner | first4 = S.| authorlink4 = Steven E. Brenner | last5 = Chervitz | first5 = S. | last6 = Dagdigian | first6 = C. | last7 = Fuellen | first7 = G. | last8 = Gilbert | first8 = J. | last9 = Korf | first9 = I. | last10 = Lapp | first10 = H. | last11 = Lehväslaiho | first11 = H. | last12 = Matsalla | first12 = C. | last13 = Mungall | first13 = C. J. | last14 = Osborne | first14 = B. I. | last15 = Pocock | first15 = M. R. | last16 = Schattner | first16 = P. | last17 = Senger | first17 = M. | last18 = Stein | first18 = L. D. | authorlink18 = Lincoln Stein| last19 = Stupka | first19 = E. | last20 = Wilkinson | first20 = M. D. | last21 = Birney | first21 = E. | authorlink21 = Ewan Birney| title = The BioPerl Toolkit: Perl Modules for the Life Sciences | doi = 10.1101/gr.361602 | journal = Genome Research | volume = 12 | issue = 10 | pages = 1611–1618 | year = 2002 | pmid = 12368254 | pmc =187536 }}
5. ^{{cite thesis|degree=PhD|first=Steven Elliot|last=Brenner|title=Molecular propinquity: evolutionary and structural relationships of proteins|publisher=University of Cambridge|date=1996|id={{EThOS|uk.bl.ethos.596888}}|url=http://ulmss-newton.lib.cam.ac.uk/vwebv/holdingsInfo?bibId=17617|website=lib.cam.ac.uk|oclc=879392272}}
6. ^{{cite web|url=http://compbio.berkeley.edu/people/brenner/ |title=About Steven E. Brenner|website=compbio.berkeley.edu}}
7. ^{{Cite journal |last1 = Murzin |first1 = A. G. |last2 = Brenner |first2 = S. |authorlink2 = Steven E. Brenner |last3 = Hubbard |first3 = T. |authorlink3 = Tim Hubbard |last4 = Chothia |first4 = C. |authorlink4 = Cyrus Chothia |title = SCOP: A structural classification of proteins database for the investigation of sequences and structures |journal = Journal of Molecular Biology |volume = 247 |issue = 4 |pages = 536–540 |year = 1995 |doi = 10.1016/S0022-2836(05)80134-2 |pmid = 7723011 |pmc = |url = http://scop.mrc-lmb.cam.ac.uk/scop/ref/1995-jmb-scop.pdf |deadurl = yes |archiveurl = https://web.archive.org/web/20120426170732/http://scop.mrc-lmb.cam.ac.uk/scop/ref/1995-jmb-scop.pdf |archivedate = 2012-04-26 |df = }}
8. ^{{cite web|title=Overton Prize winners|url=http://www.iscb.org/iscb-awards/overton-prize}}
{{ISCB Fellows}}{{Overton Prize}}{{Authority control}}{{DEFAULTSORT:Brenner, Steven}}

10 : University of California, Berkeley faculty|Bioinformaticians|Living people|21st-century American biologists|Overton Prize winners|Harvard University alumni|Alumni of the University of Cambridge|Project Steve|Fellows of the International Society for Computational Biology|Year of birth missing (living people)

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