请输入您要查询的百科知识:

 

词条 Susan Gottesman
释义

  1. Life

  2. Awards and honors

  3. Selected publications

  4. References

{{Use mdy dates|date=October 2018}}{{Infobox scientist
| name = Susan Gottesman
| image = Susan Gottesman NIH.jpg
| image_size = 120x
| alt = NIH photo of Susan Gottesman
| birth_date = {{birth date and age|1945|05|19}}
| birth_place = New York, New York
| residence = Bethesda, Maryland
| fields =
  • Genetics
  • Microbial biology

| workplaces =
  • National Institutes of Health

}}
| alma_mater =
  • Radcliffe College
  • Harvard University

| thesis_year = 1972
| known_for =
  • Bacterial small RNAs
  • Proteases and their function in ATP-hydrolysis.
  • Discovered central features of new family of proteases requiring energy for their function in the form of ATP-hydrolysis.
      }}  }}

Susan Gottesman is microbiologist at the National Cancer Institute (NCI), which is part of the National Institutes of Health. She is a pioneer in the area of biological regulation in which enzymes that destroy specific other proteins, called proteases, play a central role inside the cell. She discovered and elucidated the central features of a new family of proteases that require energy for their function in the form of ATP-hydrolysis.[1] She has also played a major role in the discovery and characterization of bacterial small RNAs.

Life

Gottesman was born on May 19, 1945, in New York. Her father was trained as an accountant and ran a company that made rotisseries and other small appliances. Her mother was a high school teacher and later became a guidance counselor.[1]

Gottesman received a B.A. in biochemical sciences in 1967 from Radcliffe College and a Ph.D. in microbiology from Harvard University in 1972. She did her postdoctoral training from 1971 to 1974 in NCI's Laboratory of Molecular Biology. From 1974 to 1976, she was a research associate at the Massachusetts Institute of Technology before returning as a senior investigator to NCI’s Laboratory of Molecular Biology. She is co-chief of that Laboratory and head of its Biochemical Genetics Section.[2]

Awards and honors

  • Elected to the National Academy of Sciences in 1998.[3]
  • Elected to the American Academy of Arts and Sciences in 1999.[4]
  • Elected to the American Academy of Microbiology (AAM) in 2009.[5]
  • American Society for Microbiology (ASM) Abbott-ASM Lifetime Achievement Award in 2011.[6]
  • Selman A. Waksman Award in Microbiology in 2015 for a major advance in the field of microbiology.[7]

Selected publications

  • {{cite journal|last1=Battesti|first1=A|last2=Hoskins|first2=JR|last3=Tong|first3=S|last4=Milanesio|first4=P|last5=Mann|first5=JM|last6=Kravats|first6=A|last7=Tsegaye|first7=YM|last8=Bougdour|first8=A|last9=Wickner|first9=S|last10=Gottesman|first10=S|title=Anti-adaptors provide multiple modes for regulation of the RssB adaptor protein.|journal=Genes & Development|date=December 15, 2013|volume=27|issue=24|pages=2722–35|pmid=24352426|doi=10.1101/gad.229617.113|pmc=3877760}}
  • {{cite journal|last1=Zhang|first1=A|last2=Schu|first2=DJ|last3=Tjaden|first3=BC|last4=Storz|first4=G|last5=Gottesman|first5=S|title=Mutations in interaction surfaces differentially impact E. coli Hfq association with small RNAs and their mRNA targets.|journal=Journal of Molecular Biology|date=October 9, 2013|volume=425|issue=19|pages=3678–97|pmid=23318956|doi=10.1016/j.jmb.2013.01.006|pmc=3640674}}
  • {{cite journal|last1=Soper|first1=T|last2=Mandin|first2=P|last3=Majdalani|first3=N|last4=Gottesman|first4=S|last5=Woodson|first5=SA|title=Positive regulation by small RNAs and the role of Hfq.|journal=Proceedings of the National Academy of Sciences of the United States of America|date=May 25, 2010|volume=107|issue=21|pages=9602–7|pmid=20457943|doi=10.1073/pnas.1004435107|pmc=2906882}}
  • {{cite journal|last1=Battesti|first1=A|last2=Majdalani|first2=N|last3=Gottesman|first3=S|title=The RpoS-mediated general stress response in Escherichia coli.|journal=Annual Review of Microbiology|date=2011|volume=65|pages=189–213|pmid=21639793|doi=10.1146/annurev-micro-090110-102946}}
  • {{cite journal|last1=De Lay|first1=N|last2=Gottesman|first2=S|title=A complex network of small non-coding RNAs regulate motility in Escherichia coli.|journal=Molecular Microbiology|date=November 2012|volume=86|issue=3|pages=524–38|pmid=22925049|doi=10.1111/j.1365-2958.2012.08209.x}}

References

1. ^{{cite web|last1=Gottesman|first1=Susan|author2=Gant, Jason|title=NCI Laboratory of Molecular Biology Oral History Project|url=http://history.nih.gov/archives/downloads/2008%2010%2001%20Susan%20Gottesman%201%20-%20Oral%20History%20Transcript.pdf|date=October 1, 2008}}
2. ^{{cite web|last1=Gottesman|first1=Susan|url=http://irp.nih.gov/pi/susan-gottesman|title=Susan Gottesman, Ph.D.}}
3. ^{{cite web|last1=National Academy of Sciences|title=Susan Gottesman|url=http://www.nasonline.org/member-directory/members/3005878.html|publisher=National Academy of Sciences|accessdate=March 15, 2015}}
4. ^{{cite web|last1=American Academy of Arts & Sciences|title=Dr. Susan Gottesman|url=https://www.amacad.org/content/system/search.aspx?s=susan+gottesman#srConstOverview|publisher=American Academy of Arts & Sciences|accessdate=March 15, 2015}}
5. ^{{cite journal|last1=American Society for Microbiology|title=American Academy of Microbiology (AAM) 2009 Election Results|journal=Microbe News|date=2009|issue=April|url=http://www.microbemagazine.org/index.php?option=com_content&view=article&id=292:american-academy-of-microbiology-aam-2009-election-results&catid=125&Itemid=230|accessdate=March 15, 2015}}
6. ^{{cite journal|last1=American Society for Microbiology|title=ASM News, 2011 General Meeting Awards|journal=Microbe Magazine|date=2011|issue=April|url=http://www.microbemagazine.org/index.php?option=com_content&view=article&id=3318:2011-general-meeting-awards&catid=734&Itemid=948|accessdate=March 15, 2015}}
7. ^{{cite web|last1=National Academy of Sciences|title=Selman A. Waksman Award in Microbiology|url=http://www.nasonline.org/about-nas/awards/waksman-award-in-microbiology.html|publisher=National Academy of Sciences|accessdate=March 15, 2015}}
{{commons category|Susan Gottesman}}{{Authority control}}{{DEFAULTSORT:Gottesman, Susan}}

8 : Radcliffe College alumni|Harvard University alumni|1945 births|Women microbiologists|Scientists from New York City|American microbiologists|Living people|NIH Women Scientists Project

随便看

 

开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。

 

Copyright © 2023 OENC.NET All Rights Reserved
京ICP备2021023879号 更新时间:2024/9/27 5:52:21