| 释义 |
- Early career
- Career
- Career history
- Awards
- Selected publications
- Notes and references
- External links
{{Use dmy dates|date=August 2016}}Susan M. Gasser is a professor of molecular biology at the University of Basel. She is currently the director of Friedrich Miescher Institute for Biomedical Research since November 2004.[1]Early careerSusan Gasser received her doctorate at the University of Basel in Biochemistry for the development of an in vitro system for the import of mitochondrial proteins with Gottfried (Jeff) Schatz. She studied the long-range folding of the genome in flies and human cells as a post-doctoral fellow at the University of Geneva with Ulrich K. Laemmli .[1][2] CareerGasser presently holds a professorship at the University of Basel and runs a research laboratory at the FMI as well as leading the institute. From 1986 to 2001, Gasser led a research group at the Swiss Institute for Experimental Cancer Research. She discovered and documented the clustering of yeast telomeres at the nuclear envelope, and elucidated the role of this subnuclear distribution in heritable gene repression using a combined genetic and fluorescence microscopy approach. From 2001 to 2004, Gasser was a professor of Molecular Biology at the University of Geneva. Since 2004, she is the Director of the Friedrich Miescher Institute in Basel, and Professor of Molecular Biology at the University of Basel. Gasser has served on review boards and advisory councils throughout Switzerland and Europe.[1][2][6] Career history- 1977-1979: University of Chicago, Illinois, United States, Bachelor of Arts with honours in biophysics[3]
- 1979-1982: University of Basel, PhD Magna Cum Laude in biochemistry, thesis advisor: Prof. G. Schatz[3]
- 1983-1986: maître assistant, Prof. U. K. Laemmli, University of Geneva, Department of Molecular Biology[3]
- 1986-1990: junior group leader, Swiss Institute for Experimental Cancer Research[3]
- 1991-2001: senior group leader, Swiss Institute for Experimental Cancer Research[3]
- 2001-2004: full professor, Department of Molecular Biology, University of Geneva, Geneva[3]
- Since December 2004: director of the Friedrich Miescher Institute for Biomedical Research, Basel[3]
- Since January 2005: full professor in molecular biology, University of Basel[3]
Awards- 2016 Honorary Doctorate, Charles University, Prague, Czech Republic[4]
- 2016 Lee Hartwell Award of the Genetics Society of America
- 2014 Doctorat Honoris causa, University of Lausanne
- 2013 Member of the EC Presidents Science and Technology advisory Council (PSTAC)[5]
- 2013 Weizmann Institute, Women in Science Award[5]
- 2012 EMBO/FEBS Women in Science Award[5][6]
- 2011 Prix International de l'INSERM, France[5]
- 2009 Election to American Association for the Advancement of Science[5]
- 2009 London Royal Society of Chemistry "Nucleic Acid" Award[5]
- 2007 Election to German Academy of Science, Leopoldina[5]
- 2006 Election to Academy of Medical Sciences, Switzerland[5]
- 2006 Gregor Mendel Medal, Czech Academy of Science[5]
- 2006 Otto Naegeli Prize for Biomedical Research, Switzerland[5]
- 2005 Foreign member, Académie des Sciences, Institut de France[5]
- 1999 Medal of Honor, 3rd Medical Faculty of Charles University, Prague[5]
- 1998 Election to Academia Europaea[5]
- 1994 Friedrich Miescher Prize, Swiss Society for Biochemistry[5]
- 1993 Member, EMBO[1]
- 1991 National Latsis Prize, Swiss National Science Foundation[5]
Selected publications- 2013 TORC2 signaling pathway guarantees genome stability in face of DNA strand breaks. Mol Cell, 51:829-839, Shimada K, Fillipuzzi I, Stahl M, Helliwell SB, Seeber A, Loewith R, Movva R, Gasser SM[7]
- 2013 The shelterin protein POT-1 anchors C. elegans telomeres through SUN-1 at the nuclear periphery. J Cell Biol, 203:727-35, Ferreira HC, Towbin BD, Jegou T, Gasser SM[7]
- 2013 Checkpoint kinases and nucleosome remodelers enhance global chromatin mobility in response to DNA damage. Genes Dev, 27:1999-2008. doi:10.1101/gad.222992.113, Seeber A, Dion V, Gasser SM [7]
- 2013 Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. EMBO Rep. 14:984-991, Dion V, Kalck V, Seeber A, Schleker T, Gasser SM[7]
- 2013 SIR proteins and the assembly of silent chromatin in budding yeast. Annu Rev Genet. 47:275-306, Kueng S, Oppikofer M, Gasser SM [7]
- 2013 Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. EMBO J. 32:437-449, Oppikofer M, Kueng S, Keusch JJ, Hassler M, Ladurner A, Gut H, Gasser SM [7]
- 2013 Promoter- and RNA polymerase II-dependent hsp-16 gene association with nuclear pores in Caenorhabditis elegans. J Cell Biol, 200:589-604 SMG is corresponding author, Rohner S, Kalck V, Wang FF, Ikegami K, Lieb JD, Gasser SM, Meister P [7]
- 2012 Step-wise methylation of histone H3K9 positions chromosome arms at the nuclear periphery in C. elegans embryos. Cell, 150:934-947, Towbin BD, Gonzalez-Aguilera C, Sack R, Gaidatzis D, Kalck V, Meister P, Askjaer P, Gasser SM [7]
- 2012 Increased dynamics of double strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nat. Cell Biol. 14:502-509, Dion V, Kalck V, Horigome C, Towbin BD, Gasser SM[7]
- 2012 Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes Dev 26:369-383, Neumann FR, Dion V, Gehlen L, Tsai-Pflugfelder M, Schmid R, Taddei A, Gasser SM[7]
Notes and references1. ^1 2 3 {{cite web|url=http://www.fmi.ch/research/groupleader/website/gasserlab/susangasser.php|accessdate=24 July 2015|title=Susan Gasser}}
2. ^1 {{cite web|url=https://ch.linkedin.com/in/smgasser|title=Susan M. Gasser Profile|accessdate=29 July 2015}}
3. ^1 2 3 4 5 6 7 8 {{cite web|url=http://www.cellplasticity.org/about/members/gasser/|accessdate=29 July 2015|title=Coordinator:Prof. Dr.Susan Gasser|deadurl=yes|archiveurl=https://web.archive.org/web/20160304125655/http://www.cellplasticity.org/about/members/gasser/|archivedate=4 March 2016|df=dmy-all}}
4. ^{{cite web|url=https://www.unibas.ch/de/Aktuell/News/Uni-People/Susan-Gasser-erhaelt-Ehrendoktor-der-Prager-Karls-Universitaet.html?pk_campaign=uninews&pk_kwd=161110|title=Susan Gasser erhält Ehrendoktor der Prager Karls-Universität|website=www.unibas.ch}}
5. ^1 2 3 4 5 6 7 8 9 10 11 12 13 14 {{cite web|url=https://www.fmi.ch/research/groupleader/biography/?group=42|title=Biography|accessdate=26 July 2015}}
6. ^{{cite web|url=http://www.embo.org/news/press-releases/press-releases-2012/susan-m-gasser-to-receive-the-2012-febs-embo-women-in-science-award|accessdate=28 July 2015|title=Susan M. Gasser to receive the 2012 FEBS/EMBO Women in Science Award}}
7. ^1 2 3 4 5 6 7 8 9 {{cite web|url=https://www.fmi.ch/research/groupleader/publications/?group=42|title=List Of Selected Publications|accessdate=7 August 2015}}
External links- Research Europe
- Gasser's Lab
{{authority control}}{{DEFAULTSORT:Gasser, Susan M.}} 16 : Swiss biologists|Molecular biologists|Swiss medical researchers|Living people|Swiss women scientists|Women biologists|Women medical researchers|University of Basel faculty|University of Basel alumni|20th-century Swiss scientists|21st-century Swiss scientists|20th-century biologists|21st-century biologists|20th-century women scientists|21st-century women scientists|Year of birth missing (living people) |