| 词条 | Sutezolid |
| 释义 |
| ImageFile = Sutezolid structure.svg | ImageSize = 250px | ImageAlt = | IUPACName = N-({(5S)-3-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]-2-oxo-oxazolidin-5-yl}methyl) acetamide | OtherNames = |Section1={{Chembox Identifiers | CASNo = | PubChem = 465951 | KEGG = D10167 | ChemSpiderID = 409595 | SMILES = CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(c(c2)F)N3CCSCC3 | InChI = 1/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 | InChIKey = FNDDDNOJWPQCBZ-ZDUSSCGKBM | StdInChI = 1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 | StdInChIKey = FNDDDNOJWPQCBZ-ZDUSSCGKSA-N }} |Section2={{Chembox Properties | Formula = | MolarMass = | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }} Sutezolid (PNU-100480, PF-02341272) is an oxazolidinone antibiotic currently in development as a treatment for extensively drug-resistant tuberculosis. It differs from linezolid by replacement of the morpholine oxygen with a sulfur atom. Notes[https://www.ncbi.nlm.nih.gov/pubmed/22279595 Rapid evaluation in whole blood culture of regimens for XDR-TB containing PNU-100480 (sutezolid), TMC207, PA-824, SQ109, and pyrazinamide] {{Protein synthesis inhibitor antibiotics}}{{Antibiotic-stub}} 3 : Fluoroarenes|Oxazolidinone antibiotics|Thiomorpholines |
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