Thomas Busby may refer to:

• Thomas Busby (soldier) (1735–1798), Irish soldier
• Thomas Busby (composer) (1755–1838), English composer
• Thomas Busby (Lower Canada politician) (1768–1836), merchant and political figure in Lower Canada
• T. Jeff Busby (1884–1964), U.S. Representative from Mississippi
• Tom Busby (1936–2003), Canadian actor
• the murderer said to have cursed an allegedly haunted chair

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