Thomas Mackworth was an English politician.

Thomas Mackworth may also refer to:

• Sir Thomas Mackworth, 1st Baronet (d. 1626), of the Mackworth Baronets
• Sir Thomas Mackworth, 3rd Baronet (1624-1694), of the Mackworth Baronets, MP for Rutland (UK Parliament constituency)
• Sir Thomas Mackworth, 4th Baronet (d. 1745), of the Mackworth Baronets, MP for Rutland (UK Parliament constituency)
• Sir Thomas Mackworth, 5th Baronet (d. 1769), of the Mackworth Baronets

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