词条 | Tienoxolol |
释义 |
| ImageFile = Tienoxolol.svg | ImageSize = 200px | ImageAlt = | IUPACName = Ethyl 2-[3-(tert-butylamino)-2-hydroxypropoxy]-5-(thiophene-2-carbonylamino)benzoate | OtherNames = |Section1={{Chembox Identifiers | CASNo = | PubChem = 65678 | ChemSpiderID = 59107 | InChI = 1/C21H28N2O5S/c1-5-27-20(26)16-11-14(23-19(25)18-7-6-10-29-18)8-9-17(16)28-13-15(24)12-22-21(2,3)4/h6-11,15,22,24H,5,12-13H2,1-4H3,(H,23,25) | InChIKey = PHMRLCQEIQGCHH-UHFFFAOYAL | StdInChI = 1S/C21H28N2O5S/c1-5-27-20(26)16-11-14(23-19(25)18-7-6-10-29-18)8-9-17(16)28-13-15(24)12-22-21(2,3)4/h6-11,15,22,24H,5,12-13H2,1-4H3,(H,23,25) | StdInChIKey = PHMRLCQEIQGCHH-UHFFFAOYSA-N | SMILES = CCOC(=O)C1=C(C=CC(=C1)NC(=O)C2=CC=CS2)OCC(CNC(C)(C)C)O}} |Section2={{Chembox Properties | C=21 | H=28 | N=2 | O=5 | S=1 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}Tienoxolol is a beta adrenergic receptor antagonist.[1] References1. ^{{cite journal|pmid=22027392|year=2012|last1=Mahé|first1=N|last2=Do|first2=B|last3=Nicolaï|first3=B|last4=Rietveld|first4=IB|last5=Barrio|first5=M|last6=Tamarit|first6=JL|last7=Céolin|first7=R|last8=Guéchot|first8=C|last9=Teulon|first9=JM|title=Crystal structure and solid-state studies of aged samples of tienoxolol, an API designed against hypertension|volume=422|issue=1–2|pages=47–51|doi=10.1016/j.ijpharm.2011.10.025|journal=International Journal of Pharmaceutics|hdl=2117/14578}} {{Adrenergics}}{{organic-compound-stub}}{{pharma-stub}} 3 : Beta blockers|Thiophenes|Ethyl esters |
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