| 词条 | Tobias Walther |
| 释义 |
Dr. Walther’s laboratory research seeks to understand the mechanisms that regulate lipid metabolism, lipid storage, and lipid function in membranes or as signaling molecules.[3] Dr. Walther’s research is focused on the mechanisms by which cells regulate their lipid content and the impact of intracellular lipids on cellular functioning.[4] At Yale, Dr. Walther positioned his laboratory at the forefront of the rapidly growing field of lipid droplet biology.[5][6] His group has extensively studied proteins required to adjust lipid droplet size and composition according to the cellular state. Additionally, his research has focused on organelle biogenesis and membrane biology. At Yale, Dr. Walther also oversaw the High Throughput Cell Biology Center at Yale's West Campus. At Harvard, Dr. Walther is working in a scientific partnership with Dr. Robert V. Farese, Jr., on the biochemistry, cell biology, and genetics of lipid metabolism and homeostasis Farese-Walther Lab. In their research, Farese and Walther have been using a variety of state-of-the systems biology approaches, such as mass-spectrometry based proteomics or high content screening. EducationDr. Walther received his PhD in biology from the European Molecular Biology Laboratory and Ludwig-Maximilians University in Munich in 2002. Dr. Walther then joined the Department of Biochemistry and Biophysics at the University of California, San Francisco, to complete his post-doctoral studies. After completion of his postdoctoral training, Dr. Walther became Group Leader at the Max Planck Institute of Biochemistry in Martinsried, Germany. In 2010, Dr. Walther relocated his lab from Germany to the United States and was appointed as an Associate Professor of Cell Biology at the Yale School of Medicine. References1. ^HSPH Faculty Page for Tobias C. Walther 2. ^Hathaway B, Faculty in the News: Not all fat is packaged the same way, Yale researchers find, Cell Biology, Yale School of Medicine, Thursday, February 14, 2013, accessed July 7, 2014 3. ^Lipid Pathways in Biology and Disease (C3), Conference organized by Michael P. Czech, Tobias C. Walther and Morris J. Birnbaum, March 19—24, 2014, Royal Dublin Society, Dublin, Ireland 4. ^Website of The Walther Lab at Yale 5. ^Lipid droplet biology, Mathias Beller page, Max-Planck-Institut für biophysikalische Chemie website 6. ^Ohsaki1 Y, Suzuki1 M, Fujimoto1 T, Open Questions in Lipid Droplet Biology, Chemistry & Biology, 2014 (January 16), 21(1):86–96, DOI: 10.1016/j.chembiol.2013.08.009 External links
6 : Living people|Harvard University faculty|Ludwig Maximilian University of Munich alumni|University of California, San Francisco alumni|Yale School of Medicine faculty|Year of birth missing (living people) |
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