词条 | Tozasertib |
释义 | {{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 449871325 | ImageFile=Tozasertib.svg | ImageSize=200px | IUPACName=N-[4-[4-(4-Methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide | OtherNames= |Section1={{Chembox Identifiers | IUPHAR_ligand = 5718 | CASNo=639089-54-6 | CASNo_Ref = {{cascite|correct|CAS}} | PubChem=5494449 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = 234335M86K | SMILES=CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)SC4=CC=C(C=C4)NC(=O)C5CC5 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 4591897 | InChI = 1/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29) | InChIKey = GCIKSSRWRFVXBI-UHFFFAOYAL | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = GCIKSSRWRFVXBI-UHFFFAOYSA-N | RTECS = | MeSHName = | ChEBI = | KEGG_Ref = {{keggcite|changed|kegg}} | KEGG = D08279 |Section2={{Chembox Properties | C=23 | H=28 | N=8 | O=1 | S=1 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Tozasertib (VX-680) is an aurora inhibitor. {{antineoplastic-drug-stub}} 6 : Protein kinase inhibitors|Pyrimidines|Thioethers|Pyrazoles|Piperazines|Cyclopropanes |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。