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词条 Tozasertib
释义 {{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 449871325
| ImageFile=Tozasertib.svg
| ImageSize=200px
| IUPACName=N-[4-[4-(4-Methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide
| OtherNames=
|Section1={{Chembox Identifiers
| IUPHAR_ligand = 5718
| CASNo=639089-54-6
| CASNo_Ref = {{cascite|correct|CAS}}
| PubChem=5494449
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = 234335M86K
| SMILES=CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)SC4=CC=C(C=C4)NC(=O)C5CC5
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4591897
| InChI = 1/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)
| InChIKey = GCIKSSRWRFVXBI-UHFFFAOYAL
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = GCIKSSRWRFVXBI-UHFFFAOYSA-N
| RTECS =
| MeSHName =
| ChEBI =
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = D08279
|Section2={{Chembox Properties
| C=23 | H=28 | N=8 | O=1 | S=1
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}

Tozasertib (VX-680) is an aurora inhibitor.

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6 : Protein kinase inhibitors|Pyrimidines|Thioethers|Pyrazoles|Piperazines|Cyclopropanes

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