| 词条 | Transplant glomerulopathy |
| 释义 |
| name = Transplant glomerulopathy | synonyms = | image = Transplant_glomerulopathy_-_very_high_mag.jpg | caption = Micrograph showing a glomerulus with changes characteristic of a transplant glomerulopathy. PAS stain. | pronounce = | field = Pathology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}Transplant glomerulopathy (TG) is a disease of the glomeruli in transplanted kidneys. It is a type of renal injury often associated with chronic antibody-mediated rejection. However, transplant glomerulopathy is not specific for chronic antibody-mediated rejection; it may be the result of a number of disease processes affecting the glomerular endothelium.[1] PathologyIt is characterized by glomerular basement membrane thickening (referred to as tram-tracking of the basement membrane), increased mesangial matrix and segmental and global glomerulosclerosis. The differential diagnosis of tram-tracking includes membranoproliferative glomerulonephritis (especially hepatitis C), and thrombotic microangiopathies.[1] See also
References1. ^1 {{Cite journal | last1 = Haas | first1 = M. | title = Transplant glomerulopathy: it's not always about chronic rejection. | journal = Kidney Int | volume = 80 | issue = 8 | pages = 801–3 |date=Oct 2011 | doi = 10.1038/ki.2011.192 | PMID = 21960169 }} External links{{Medical resources| DiseasesDB = | ICD10 = | ICD9 = | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = }} 1 : Kidney diseases |
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