“TRNA (adenine22-N1)-methyltransferase”的意思、由来-开放百科全书

词条

TRNA (adenine22-N1)-methyltransferase

释义

References
External links

{{Infobox enzyme
| Name = TRNA (adenine²²-N¹)-methyltransferase
| EC_number = 2.1.1.217
| CAS_number =
| IUBMB_EC_number = 2/1/1/217
| GO_code =
| image =
| width =
| caption =
}}TRNA (adenine²²-N¹)-methyltransferase ({{EC number|2.1.1.217}}, TrmK, YqfN, Sp1610 (gene), tRNA: m1A22 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine²²-N¹)-methyltransferase.^[1]^[2] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenine²² in tRNA S-adenosyl-L-homocysteine + N¹-methyladenine²² in tRNA

The enzyme specifically methylates adenine²² in tRNA.

References

1. ^{{cite journal | vauthors = Ta HM, Kim KK | title = Crystal structure of Streptococcus pneumoniae Sp1610, a putative tRNA methyltransferase, in complex with S-adenosyl-L-methionine | journal = Protein Science | volume = 19 | issue = 3 | pages = 617–24 | date = March 2010 | pmid = 20052680 | pmc = 2866285 | doi = 10.1002/pro.319 }}
2. ^{{cite journal | vauthors = Roovers M, Kaminska KH, Tkaczuk KL, Gigot D, Droogmans L, Bujnicki JM | title = The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK) | journal = Nucleic Acids Research | volume = 36 | issue = 10 | pages = 3252–62 | date = June 2008 | pmid = 18420655 | pmc = 2425500 | doi = 10.1093/nar/gkn169 }}

External links

{{MeshName|TRNA+(adenine22-N1)-methyltransferase}}

1 : EC 2.1.1

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