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词条 Tyrosine ammonia-lyase
释义

  1. See also

  2. References

  3. External links

{{Infobox enzyme
| Name = Tyrosine ammonia lyase
| EC_number = 4.3.1.23
| CAS_number =
| IUBMB_EC_number =
| GO_code =
| image =
| width =
| caption =
}}Tyrosine ammonia lyase (L-tyrosine ammonia-lyase, TAL or Tyrase) is an enzyme in the natural phenols biosynthesis pathway. It transforms L-tyrosine into p-coumaric acid.[1][2][3]

   + Ammonia + H+

See also

  • EC 4.3.1.24 (phenylalanine ammonia-lyase)
  • EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase)

References

1. ^{{cite journal | vauthors = Louie GV, Bowman ME, Moffitt MC, Baiga TJ, Moore BS, Noel JP | title = Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases | journal = Chemistry & Biology | volume = 13 | issue = 12 | pages = 1327–38 | date = December 2006 | pmid = 17185228 | pmc = 2859959 | doi = 10.1016/j.chembiol.2006.11.011 }}
2. ^{{cite journal | vauthors = Watts KT, Mijts BN, Lee PC, Manning AJ, Schmidt-Dannert C | title = Discovery of a substrate selectivity switch in tyrosine ammonia-lyase, a member of the aromatic amino acid lyase family | journal = Chemistry & Biology | volume = 13 | issue = 12 | pages = 1317–26 | date = December 2006 | pmid = 17185227 | doi = 10.1016/j.chembiol.2006.10.008 }}
3. ^{{cite journal | vauthors = Schwede TF, Rétey J, Schulz GE | title = Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile | journal = Biochemistry | volume = 38 | issue = 17 | pages = 5355–61 | date = April 1999 | pmid = 10220322 | doi = 10.1021/bi982929q }}

External links

  • {{MeshName|Tyrosine+ammonia-lyase}}
  • [https://web.archive.org/web/20090513052346/http://www.hhmi.org/news/popups/noel20061222_pop.html www.hhmi.org]
{{Carbon-nitrogen lyases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{enzyme-stub}}

2 : EC 4.3.1|Hydroxycinnamic acids metabolism

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