词条 | Tyrosine ammonia-lyase |
释义 |
| Name = Tyrosine ammonia lyase | EC_number = 4.3.1.23 | CAS_number = | IUBMB_EC_number = | GO_code = | image = | width = | caption = }}Tyrosine ammonia lyase (L-tyrosine ammonia-lyase, TAL or Tyrase) is an enzyme in the natural phenols biosynthesis pathway. It transforms L-tyrosine into p-coumaric acid.[1][2][3] + Ammonia + H+ See also
References1. ^{{cite journal | vauthors = Louie GV, Bowman ME, Moffitt MC, Baiga TJ, Moore BS, Noel JP | title = Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases | journal = Chemistry & Biology | volume = 13 | issue = 12 | pages = 1327–38 | date = December 2006 | pmid = 17185228 | pmc = 2859959 | doi = 10.1016/j.chembiol.2006.11.011 }} 2. ^{{cite journal | vauthors = Watts KT, Mijts BN, Lee PC, Manning AJ, Schmidt-Dannert C | title = Discovery of a substrate selectivity switch in tyrosine ammonia-lyase, a member of the aromatic amino acid lyase family | journal = Chemistry & Biology | volume = 13 | issue = 12 | pages = 1317–26 | date = December 2006 | pmid = 17185227 | doi = 10.1016/j.chembiol.2006.10.008 }} 3. ^{{cite journal | vauthors = Schwede TF, Rétey J, Schulz GE | title = Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile | journal = Biochemistry | volume = 38 | issue = 17 | pages = 5355–61 | date = April 1999 | pmid = 10220322 | doi = 10.1021/bi982929q }} External links
2 : EC 4.3.1|Hydroxycinnamic acids metabolism |
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