| 词条 | UNC93A |
| 释义 |
Unc93A is a major facilitator superfamily (MFS), and a putative solute carrier in humans.[2][3] It belongs to the atypical SLCs UNC93A is closely related to Unc93B1 and MFSD11.[4][5] UNC93A is affected by amino acid deprivation in cell cortex cultures[3][4] and starvation in in vivo samples.[4] It is expressed in neurons, with staining close to the plasma membrane.[4] Read also [6][7] for functional studies in C.elegans. References1. ^{{cite web | title = Entrez Gene: Unc-93 homolog A (C. elegans) | url = https://www.ncbi.nlm.nih.gov/gene/54346 }} 2. ^1 {{cite journal | vauthors = Perland E, Fredriksson R | title = Classification Systems of Secondary Active Transporters | journal = Trends in Pharmacological Sciences | volume = 38 | issue = 3 | pages = 305–315 | date = March 2017 | pmid = 27939446 | doi = 10.1016/j.tips.2016.11.008 }} 3. ^1 {{cite journal | vauthors = Perland E, Bagchi S, Klaesson A, Fredriksson R | title = Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression | journal = Open Biology | volume = 7 | issue = 9 | date = September 2017 | pmid = 28878041 | pmc = 5627054 | doi = 10.1098/rsob.170142 | page=170142}} 4. ^1 2 3 {{cite journal | vauthors = Ceder MM, Lekholm E, Hellsten SV, Perland E, Fredriksson R | title = The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice | language = English | journal = Frontiers in Molecular Neuroscience | volume = 10 | pages = 351 | date = 2017 | pmid = 29163028 | doi = 10.3389/fnmol.2017.00351 | pmc=5671512}} 5. ^{{cite journal | vauthors = Perland E, Lekholm E, Eriksson MM, Bagchi S, Arapi V, Fredriksson R | title = The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis | journal = PLOS One | volume = 11 | issue = 6 | pages = e0156912 | date = 2016 | pmid = 27272503 | pmc = 4896477 | doi = 10.1371/journal.pone.0156912 }} 6. ^{{cite journal | vauthors = Levin JZ, Horvitz HR | title = The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction | journal = The Journal of Cell Biology | volume = 117 | issue = 1 | pages = 143–55 | date = April 1992 | pmid = 1313436 | pmc = 2289394 | doi=10.1083/jcb.117.1.143}} 7. ^{{cite journal | vauthors = de la Cruz IP, Levin JZ, Cummins C, Anderson P, Horvitz HR | title = sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans | journal = The Journal of Neuroscience | volume = 23 | issue = 27 | pages = 9133–45 | date = October 2003 | pmid = 14534247 | doi = 10.1523/JNEUROSCI.23-27-09133.2003 }} Further reading{{refbegin}}
1 : Human proteins |
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