“Vascular corrosion casting”的意思、由来-开放百科全书

词条

Vascular corrosion casting

释义

Technique
External links
References

{{Orphan|date=July 2014}}Vascular corrosion casting uses resin to capture the 3D structure of blood vessels within human and animal tissue. It is widely used in research as a technique for obtaining the volume and surface area of the blood vessel network within an organ. The earliest known use of corrosion casting was by Robert Boyle in 1663.^[1]

Technique

Vascular corrosion casting requires the use of a solidifying material such as a resin. The most common resin used for vascular corrosion casting is Batson's 17.^[2] The process begins with the draining of blood from vessels to prevent blockage from clotting, this can be achieved by perfusing blood vessels with a physiological fluid such as phosphate buffered saline.^[3] Subsequently, the blood vessels of interest are filled with resin (or alternative solidifying material). The resin is allowed to cure resulting in the blood vessel network containing a solid plastic material. Surrounding tissue is dissolved away using a corrosive chemical, commonly potassium hydroxide. Corrosion should not affect the resin, only dissolving tissue. The final product is a 3D network of blood vessels.

External links

[https://wellcomecollection.org/articles/modelling-and-mapping/?image=6 Corrosion cast of blood vessels in the brain - Wellcome Collection]

References

1. ^J Hyrtl. Corrosions-Anatomie und ihre Ergebnisse. Braumu ̈ller, Wien, 1873.
2. ^http://www.polysciences.com/SiteData/docs/105/1ecebbad32a1c59d52b985f6c81a391e/105.pdf
3. ^{{cite journal|last1=Verli|first1=Flaviana Dornela|last2=Rossi-Schneider|first2=Tissiana Raquel|last3=Schneider|first3=Felipe LuÍs|last4=Yurgel|first4=Liliane Soares|last5=de Souza|first5=Maria Antonieta Lopes|title=Vascular Corrosion Casting Technique Steps|journal=Scanning|volume=29|issue=3|pages=128–132|doi=10.1002/sca.20051}}

1 : Angiology

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