词条 | Very-long-chain enoyl-CoA reductase |
释义 |
| Name = Very-long-chain enoyl-CoA reductase | EC_number = 1.3.1.93 | CAS_number = | IUBMB_EC_number = 1/3/1/93 | GO_code = | image = | width = | caption = }}Very-long-chain enoyl-CoA reductase ({{EC number|1.3.1.93}}, TSC13 (gene name), CER10 (gene)) is an enzyme with systematic name very-long-chain acyl-CoA:NADP+ oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction a very-long-chain acyl-CoA + NADP+ a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+ This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA. References1. ^{{cite journal | title = Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae |author1 = Kohlwein, S.D. |author2 =Eder, S. |author3 =Oh, C.S. |author4 =Martin, C.E. |author5 =Gable, K. |author6 =Bacikova, D. |author7 =Dunn, T. | journal = Mol. Cell. Biol. |year = 2001 |volume = 21 |pages = 109–125 |pmid = 11113186 |doi=10.1128/MCB.21.1.109-125.2001 |issue=1 |pmc=88785}} 2. ^{{cite journal | title = Functional characterization of the Arabidopsis thaliana orthologue of Tsc13p, the enoyl reductase of the yeast microsomal fatty acid elongating system |author1 = Gable, K. |author2 =Garton, S. |author3 =Napier, J.A. |author4 =Dunn, T.M. |journal = J. Exp. Bot. |year = 2004 |volume = 55 |pages = 543–545 |pmid = 14673020 |doi=10.1093/jxb/erh061 |issue=396}} 3. ^{{cite journal | title = Targeting of Tsc13p to nucleus-vacuole junctions: a role for very-long-chain fatty acids in the biogenesis of microautophagic vesicles |author1 = Kvam, E. |author2 =Gable, K. |author3 =Dunn, T.M. |author4 =Goldfarb, D.S. |journal = Mol. Biol. Cell |year = 2005 |volume = 16 |pages = 3987–3998 |pmid = 15958487 |doi=10.1091/mbc.E05-04-0290 |issue=9 |pmc=1196313}} 4. ^{{cite journal | title = Disruptions of the Arabidopsis Enoyl-CoA reductase gene reveal an essential role for very-long-chain fatty acid synthesis in cell expansion during plant morphogenesis |author1 = Zheng, H. |author2 =Rowland, O. |author3 =Kunst, L. |journal = Plant Cell |year = 2005 |volume = 17 |pages = 1467–1481 |pmid = 15829606 |doi=10.1105/tpc.104.030155 |issue=5 |pmc=1091768}} External links
1 : EC 1.3.1 |
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