| 词条 | Vts1 |
| 释义 |
| Symbol = Vts1 | Name = Vts1 | image = Vts1P_SRE_Recognition_SAM_domain.jpg | width = | caption = Crystal structure of Vts1p–SRE complex.[1] | Pfam = PF07647 | Pfam_clan = | InterPro = | SMART = | PROSITE = | MEROPS = | SCOP = 1b0x | TCDB = | OPM family = | OPM protein = | CAZy = | CDD = }}Vts1 is a post-transcriptional regulator that has RNA-binding Sterile alpha motif (SAM) domain.[2][3] The protein is found in Saccharomyces cerevisiae and several eukaryotes. In Saccharomyces the Vts1 impacts vesicular transport and sporulation.[4][5] InteractionsProtein-protein interactions through SAM domains participate in different regulatory activities such as signal transduction. Proteins having such domains were also shown to recognize and interact with RNA structures of similar shape to the Smaug response element (SRE).[6] Vts1 binds to RNA targets that have CUGGC on hairpin loops.[7]References1. ^{{cite journal|author1=Philip E Johnson |author2=Logan W Donaldson |lastauthoramp=yes |title=SRNA recognition by the Vts1p SAM domain.|journal=Nature Structural & Molecular Biology|date=Jan 2006|volume=13|issue=1|pages=177–178|doi=10.1038/nsmb1039}} 2. ^{{cite journal |vauthors=Bork P, Ponting CP, Hofmann K, Schultz J |title=SAM as a protein interaction domain involved in developmental regulation |journal=Protein Sci. |volume=6 |issue=1 |pages=249–253 |year=1997 |pmid=9007998 |doi=10.1002/pro.5560060128 |pmc=2143507}} 3. ^{{cite journal|author=Florian C Oberstrass, Albert Lee, Richard Stefl, Michael Janis, Guillaume Chanfreau & Frédéric H-T Allain|title=Shape-specific recognition in the structure of the Vts1p SAM domain with RNA|journal=Nature Structural & Molecular Biology |volume=13|pages=160–167|date=Jan 2006|doi=10.1038/nsmb1038|pmid=16429156}} 4. ^{{cite journal| author=Adam M. Deutschbauer, Roy M. Williams, Angela M. Chu, and Ronald W. Davis|title=Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyce scerevisiae|journal=PNAS|volume=99|issue=24|pages=15530–15535|year=November 2002|doi=10.1073/pnas.202604399|pmid=12432101|pmc=137751}} 5. ^{{cite journal|author=Meik Dilcher, Beate Köhler and Gabriele Fischer von Mollard|title=Genetic Interactions with the Yeast Q-SNARE VTI1 Reveal Novel Functions for the R-SNARE YKT6|journal=The Journal of Biological Chemistry|volume=276|pages=34537–34544|year=September 2001|doi=10.1074/jbc.M101551200|pmid=11445562}} 6. ^{{cite journal|author=Traci M Tanaka Hall|title=SAM breaks its stereotype|journal=Nature Structural & Molecular Biology|volume=10|pages=677–679|year=2003|doi=10.1038/nsb0903-677}} 7. ^{{cite journal | author=Florian C Oberstrass, Albert Lee, Richard Stefl, Michael Janis, Guillaume Chanfreau and Frédéric H-T Allain|title=Shape-specific recognition in the structure of the Vts1p SAM domain with RNA|journal=Nature Structural & Molecular Biology|volume=13|issue=2|pages=160–167|date=January 2006|doi=10.1038/nsmb1038|pmid=16429156}} 2 : Protein domains|Protein complexes |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。