词条 | Yunnanxane |
释义 |
| Name = Yunnanxane | ImageFile = Yunnanxane.svg | ImageSize = | ImageAlt = | ImageCaption = | IUPACName = | SystematicName = 2,5,10-Triacetoxytaxa-4(20),11-dien-14-yl 3-hydroxy-2-methylbutanoate | OtherNames = |Section1={{Chembox Identifiers | Abbreviations = | CASNo = 139713-81-8 | CASNo_Comment = | CASNo_Ref = {{cascite|correct|}} | CASNoOther = | PubChem = 11226788 | PubChem_Comment = | PubChem5 = | PubChem5_Comment = | PubChemOther = | ChEMBL = 245750 | ChemSpiderID = 4474732 | ChemSpiderID_Comment = | ChemSpiderID5 = | ChemSpiderIDOther = | EINECS = | EC_number = | UNNumber = | DrugBank = | KEGG = | MeSHName = | ChEBI = | RTECS = | SMILES = CC1(C)C([C@@H](OC(C)=O)C[C@@]2(C)[C@](C([C@@H](OC(C)=O)CC2)=C)([H])[C@@H]3OC(C)=O)=C(C)[C@@H](OC([C@H](C)[C@H](C)O)=O)C[C@]13[H] | InChI = | Beilstein = | Gmelin = | 3DMet = |Section2={{Chembox Properties | C=31 | H=46 | O=9 | Appearance = | Density = | MeltingPt = | MeltingPt_notes = | BoilingPt = | BoilingPt_notes = | LogP = | VaporPressure = | HenryConstant = | AtmosphericOHRateConstant = | pKa = | pKb = | Solubility = | SolubleOther = | Solvent = |Section3={{Chembox Structure | CrystalStruct = | Coordination = | MolShape = |Section5={{Chembox Thermochemistry | DeltaHc = | DeltaHf = | Entropy = | HeatCapacity = |Section6={{Chembox Pharmacology | ATCvet = | ATCCode_prefix = | ATCCode_suffix = | ATC_Supplemental = | AdminRoutes = | Bioavail = | Metabolism = | HalfLife = | ProteinBound = | Excretion = | Legal_status = | Legal_US = | Legal_UK = | Legal_AU = | Legal_CA = | Pregnancy_category = | Pregnancy_AU = | Pregnancy_US = |Section4={{Chembox Explosive | ShockSens = | FrictionSens = | DetonationV = | REFactor = |Section7={{Chembox Hazards | ExternalSDS = | EUClass = | MainHazards = | NFPA-H = | NFPA-F = | NFPA-R = | NFPA-S = | RPhrases = | SPhrases = | RSPhrases = | FlashPt = | AutoignitionPt = | ExploLimits = | LD50 = | PEL = |Section8={{Chembox Related | OtherAnions = | OtherCations = | OtherFunction = | OtherFunction_label = | OtherCompounds = }}Yunnanxane is a bioactive taxane diterpenoid first isolated from Taxus wallichiana. Yunnanxane was later isolated from cell cultures of Taxus cuspidata and Taxus chinensis. Four homologous esters of yunnanxane have also been isolated from Taxus. Yunnanxane is reported to have anticancer activity in vitro.[1][2] See also
References1. ^{{cite journal|vauthors=Chen WM, Zhang PL, Wu B, Zheng QT | title=[Studies on the chemical constituents of Taxus yunnanensis]. | journal=Yao Xue Xue Bao | year= 1991 | volume= 26 | issue= 10 | pages= 747–54 | pmid=1688071 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1688071 }} {{organic-compound-stub}}2. ^{{cite journal |vauthors=Ma W, Stahlhut RW, Adams TL, Park GL, Evans WA, Blumenthal SG, etal | title=Yunnanxane and its homologous esters from cell cultures of Taxus chinensis var. mairei. | journal=J Nat Prod | year= 1994 | volume= 57 | issue= 9 | pages= 1320–4 | pmid=7798969 | doi= 10.1021/np50111a027| pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7798969 }} 2 : Acetate esters|Taxanes |
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