词条 | 11β-Hydroxyandrostenedione |
释义 |
| ImageFile = 11β-Hydroxyandrostenedione.svg | ImageSize = 200px | ImageAlt = | IUPACName = (8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione | OtherNames = 11β-Hydroxy-4-androstenedione; 11β-Hydroxyandrost-4-ene-3,17-dione; 11β-OHA4 | Section1 = {{Chembox Identifiers | CASNo = 382-44-5 | ChEBI = 27967 | ChEMBL = 2311170 | ChemSpiderID = 84958 | PubChem = 94141 | StdInChI = 1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1 | StdInChIKey = WSCUHXPGYUMQEX-KCZNZURUSA-N | SMILES = C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CCC4=O)C)O | UNII = 41G81C896T | Section2 = {{Chembox Properties | C=19 | H=26 | O=3 | MolarMass = 302.414 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}11β-Hydroxyandrostenedione (11β-OHA4), also known as 11β-hydroxyandrost-4-ene-3,17-dione, is an endogenous, naturally occurring steroid and androgen prohormone that is produced primarily, if not exclusively, in the adrenal glands.[1] It is closely related to adrenosterone (11-ketoandrostenedione; 11-KA4), 11-ketotestosterone (11-KT), and 11-ketodihydrotestosterone (11-KDHT), which are also produced in the adrenal glands.[1] See also
References1. ^1 {{cite journal|last1=Pretorius|first1=Elzette|last2=Arlt|first2=Wiebke|last3=Storbeck|first3=Karl-Heinz|title=A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids|journal=Molecular and Cellular Endocrinology|year=2016|issn=0303-7207|doi=10.1016/j.mce.2016.08.014}} {{Steroid hormones}}{{Androgen receptor modulators}}{{DEFAULTSORT:Hydroxyandrostenedione, 11β-}}{{steroid-stub}} 7 : Alcohols|Androgens and anabolic steroids|Androstanes|Hormones of the suprarenal cortex|Ketones|Sex hormones|Steroid hormones |
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