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词条 11β-Hydroxyandrostenedione
释义

  1. See also

  2. References

{{Chembox
| ImageFile = 11β-Hydroxyandrostenedione.svg
| ImageSize = 200px
| ImageAlt =
| IUPACName = (8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
| OtherNames = 11β-Hydroxy-4-androstenedione; 11β-Hydroxyandrost-4-ene-3,17-dione; 11β-OHA4
| Section1 = {{Chembox Identifiers
| CASNo = 382-44-5
| ChEBI = 27967
| ChEMBL = 2311170
| ChemSpiderID = 84958
| PubChem = 94141
| StdInChI = 1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1
| StdInChIKey = WSCUHXPGYUMQEX-KCZNZURUSA-N
| SMILES = C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CCC4=O)C)O
| UNII = 41G81C896T
| Section2 = {{Chembox Properties
| C=19 | H=26 | O=3
| MolarMass = 302.414 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
| Section3 = {{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}11β-Hydroxyandrostenedione (11β-OHA4), also known as 11β-hydroxyandrost-4-ene-3,17-dione, is an endogenous, naturally occurring steroid and androgen prohormone that is produced primarily, if not exclusively, in the adrenal glands.[1] It is closely related to adrenosterone (11-ketoandrostenedione; 11-KA4), 11-ketotestosterone (11-KT), and 11-ketodihydrotestosterone (11-KDHT), which are also produced in the adrenal glands.[1]

See also

  • 4-Androstenedione

References

1. ^{{cite journal|last1=Pretorius|first1=Elzette|last2=Arlt|first2=Wiebke|last3=Storbeck|first3=Karl-Heinz|title=A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids|journal=Molecular and Cellular Endocrinology|year=2016|issn=0303-7207|doi=10.1016/j.mce.2016.08.014}}
{{Steroid hormones}}{{Androgen receptor modulators}}{{DEFAULTSORT:Hydroxyandrostenedione, 11β-}}{{steroid-stub}}

7 : Alcohols|Androgens and anabolic steroids|Androstanes|Hormones of the suprarenal cortex|Ketones|Sex hormones|Steroid hormones

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