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词条 1,4-Diazacycloheptane
释义

  1. Related compounds

  2. References

{{Chembox
| ImageFile = DACH.png
| ImageSize = 150px
| ImageAlt =
| IUPACName = 1,4-Diazepane
| OtherNames = {{bulletedlist|DACH|Homopiperazine}}
|Section1={{Chembox Identifiers
| CASNo = 505-66-8
| PubChem = 68163
| ChemSpiderID = 61471
| EINECS = 208-016-1
| InChI=1S/C5H12N2/c1-2-6-4-5-7-3-1/h6-7H,1-5H2
| InChIKey=FQUYSHZXSKYCSY-UHFFFAOYSA-N
| SMILES = C1CNCCNC1}}
|Section2={{Chembox Properties
| C=5|H=12|N=2
| MolarMass =
| Appearance = Colorless oily solid
| Density =
| MeltingPtC = 42
| BoilingPtC = 168-170
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}1,4-Diazacycloheptane is an organic compound with the formula (CH2)5(NH)2. This cyclic diamine is a colorless oily liquid that is soluble in polar solvents. It is studied as a chelating ligand. The N-H centers can be replaced with many other groups.[1]

It has known use in pharmaceuticals in lieu of piperazine, for example:

  1. Fasudil
  2. Bunazosin
  3. Homochlorcyclizine
  4. Homopipramol

Related compounds

  • 1,5-Diazacyclooctane

References

1. ^{{cite journal|title=Coordination chemistry of bidentate medium ring ligands (mesocycles) |author=Musker, W. Kenneth|journal=Coordination Chemistry Reviews |year=1992|volume=117|pages=133–57|doi=10.1016/0010-8545(92)80022-J}}
{{DEFAULTSORT:Diazacycloheptane, 1,4-}}

2 : Diamines|Chelating agents

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