词条 | 16α-Hydroxy-DHEA sulfate |
释义 |
| ImageFile = 16α-Hydroxy-DHEA sulfate.svg | ImageSize = 250px | ImageAlt = | IUPACName = [(3S,8R,9S,10R,13S,14S,16R)-16-Hydroxy-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate | OtherNames = 16α-Hydroxy-17-oxoandrost-5-en-3β-yl sulfate; 16α-OH-DHEA-S | Section1 = {{Chembox Identifiers | CASNo = | ChEBI = 87538 | ChemSpiderID = 24850136 | PubChem = 20848950 | StdInChI = InChI=1S/C19H28O6S/c1-18-7-5-12(25-26(22,23)24)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(20)17(19)21/h3,12-16,20H,4-10H2,1-2H3,(H,22,23,24)/t12-,13+,14-,15-,16+,18-,19-/m0/s1 | StdInChIKey = ALBNSVAJDFJRKQ-DNKQKWOHSA-N | SMILES = C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3C[C@H](C4=O)O)C)OS(=O)(=O)O | Section2 = {{Chembox Properties | C=19 | H=28 | O=6 | S=1 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}16α-Hydroxydehydroepiandrosterone sulfate (16α-OH-DHEA-S), also known as 16α-hydroxy-17-oxoandrost-5-en-3β-yl sulfate, is an endogenous, naturally occurring steroid and a metabolic intermediate in the production of estriol from dehydroepiandrosterone (DHEA) during pregnancy.[1][2] It is the C3β sulfate ester of 16α-hydroxy-DHEA.[3][4] See also
References1. ^{{cite book|author1=Jerome F. Strauss, III|author2=Robert L. Barbieri|title=Yen and Jaffe's Reproductive Endocrinology|url=https://books.google.com/books?id=KZ95AAAAQBAJ&pg=PA256|date=13 September 2013|publisher=Elsevier Health Sciences|isbn=978-1-4557-2758-2|pages=256–}} {{Steroid hormones}}{{DEFAULTSORT:Hydroxy-DHEA sulfate, 16α-}}{{steroid-stub}}2. ^{{cite book|author=Hiroshi Yamazaki|title=Fifty Years of Cytochrome P450 Research|url=https://books.google.com/books?id=9mslBAAAQBAJ&pg=PA385|date=23 June 2014|publisher=Springer|isbn=978-4-431-54992-5|pages=385–}} 3. ^{{cite book|author=Mike S. Lee|title=Mass Spectrometry Handbook|url=https://books.google.com/books?id=S6r8geKvKM8C&pg=PA320|date=8 May 2012|publisher=John Wiley & Sons|isbn=978-0-470-53673-5|pages=320–}} 4. ^{{cite book|author1=Shlomo Melmed|author2=Kenneth S. Polonsky|author3=P. Reed Larsen |author4=Henry M. Kronenberg |title=Williams Textbook of Endocrinology|url=https://books.google.com/books?id=YZ8_CwAAQBAJ&pg=PA839|date=30 November 2015|publisher=Elsevier Health Sciences|isbn=978-0-323-29738-7|pages=839–}} 6 : Alcohols|Androstanes|Steroid esters|Ketones|Steroid hormones|Sulfates |
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