| 词条 | 16β,17α-Epiestriol |
| 释义 |
| ImageFile = 16β,17α-Epiestriol.svg | ImageSize = 250px | ImageAlt = | IUPACName = (8R,9S,13S,14S,16S,17S)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol | OtherNames = | Section1 = {{Chembox Identifiers | CASNo = 793-89-5 | ChemSpiderID = 13628086 | PubChem = 21252247 | SMILES = C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@@H]([C@H]2O)O)CCC4=C3C=CC(=C4)O | InChI = 1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16+,17-,18+/m1/s1 | Section2 = {{Chembox Properties | C=18 | H=24 | O=3 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}16β,17α-Epiestriol, or 16,17-epiestriol, also known as 16β-hydroxy-17α-estradiol, as well as estra-1,3,5(10)-triene-3,16β,17α-triol, is a minor and weak endogenous steroidal estrogen that is related to 17α-estradiol and estriol.[1][2] Along with estriol, 16β,17α-epiestriol has been detected in the urine of women during the late pregnancy stage.[2] It shows preferential affinity for the ERβ over the ERα.[3] See also
References1. ^{{cite book|title=Vitamins and Hormones|url=https://books.google.com/books?id=iQZgQRUI_CgC&pg=PA233|date=18 April 1972|publisher=Academic Press|isbn=978-0-08-086626-0|pages=233–}} {{Steroid hormones}}{{Estrogen receptor modulators}}{{DEFAULTSORT:Epiestriol, 16β,17α-}}2. ^1 {{cite book|author1=Ryō Satō|author2=Ryūichi Katō|title=Microsomes, drug oxidations, and drug toxicity|url=https://books.google.com/books?id=t7PwAAAAMAAJ|year=1982|publisher=Japan Scientific Societies Press|isbn=978-0-471-87285-6|page=273}} 3. ^{{cite journal | vauthors = Zhu BT, Han GZ, Shim JY, Wen Y, Jiang XR | title = Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor alpha and beta subtypes: Insights into the structural determinants favoring a differential subtype binding | journal = Endocrinology | volume = 147 | issue = 9 | pages = 4132–50 | year = 2006 | pmid = 16728493 | doi = 10.1210/en.2006-0113 | url = }} 2 : Estranes|Estrogens |
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