The Upper Room is location of the Last Supper that Jesus Christ took with his disciples.

The Upper Room may also refer to:

• The Cenacle, the traditional site of the Last Supper.
• The Upper Room (band), a defunct UK rock music band
• The Upper Room (Devotional and Ministry Organization), a worldwide publisher of the daily devotional guide of the same name
• The Upper Room (paintings), an installation of paintings by Chris Ofili
• In the Upper Room, a ballet by U.S. choreographer Twyla Tharp, first performed in 1986
• "The Upper Room", a song made popular by Mahalia Jackson

• Asymmetric Information
• Asymmetric ion-pairing catalysis
• Asymmetric-key cryptosystem
• Asymmetric multi-core processor
• Asymmetric payoff
• Asymmetric simple exclusion process
• Asymmetric Simple Exclusion Process
• Asymmetric skirt
• Asymmetric synthesis
• Asymmetric triggerplant
• Asymmetric typography
• Asymmetric unit
• Asymmetries
• Asymmetry (album)
• Asymmetry Festival
• Asymmetry (Karnivool album)
• Asymmetry (Mallory Knox album)
• Asymmetry of the Intertropical Convergence Zone
• A Symphony in Two Flats
• A Symphony of British Music
• A Symphony of British Music (album)
• Asymphorodes acerba
• Asymphorodes acerbus
• Asymphorodes acritopterus
• Asymphorodes acrophrictis