词条 | Uridine diphosphate |
释义 |
| Verifiedfields = changed | verifiedrevid = 470620324 | ImageFile=Uridindiphosphat protoniert.svg | ImageAlt = Skeletal formula of uridine diphosphate | ImageFile1=Uridine diphosphate anion 3D ball.png | ImageAlt1=Ball-and-stick model of the UDP molecule as an anion | IUPACName=Uridine 5'-(trihydrogen diphosphate) | OtherNames= |Section1={{Chembox Identifiers | CASNo=58-98-0 | CASNo_Ref = {{cascite|correct|CAS}} | PubChem=1158 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 130266 | IUPHAR_ligand = 1749 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 19952429 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C9H12N2O6.2H3O4P/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;2*1-5(2,3)4/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);2*(H3,1,2,3,4)/t4-,6-,7-,8-;;/m1../s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = PMPFLUWUGZHTOK-WFIJOQBCSA-N | SMILES= | MeSHName=Uridine+diphosphate |Section2={{Chembox Properties | Formula=C9H14N2O12P2 | MolarMass=404.161 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Uridine diphosphate, abbreviated UDP, is a nucleotide diphosphate. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil. UDP is an important factor in glycogenesis. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, cleaving a pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. The UDP molecule is cleaved from the glucose ring during this process and can be reused by UDP-glucose pyrophosphorylase.[1][2] See also
References1. ^[https://www.uic.edu/classes/phar/phar332/Clinical_Cases/carbo%20metab%20cases/glycogen%20metab/Glycogen%20biochemistry.htm Glycogen Biochemistry] {{Nucleobases, nucleosides, and nucleotides}}{{Purinergics}}{{DEFAULTSORT:Uridine Diphosphate}}{{Biochem-stub}}2. ^Biochemistry Pathways: Polysaccharide Synthesis 3 : Nucleotides|Pyrimidinediones|Pyrophosphates |
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