USS Frederick may refer to:

• {{USS|Frederick|CA-8}} laid down in 1901 as {{USS|Maryland|ACR-8}}; renamed Frederick in 1916; decommissioned 1922
• {{USS|Frederick|LST-1184}}, a {{sclass-|Newport|tank landing ship}}, commissioned in 1970 and decommissioned in 2002

• Karlis Ozols
• Karlis Padegs
• Karlis Skrastins
• Karlis Zale
• Karl Ivanovich Rossi
• Karl Ivanovich Waeber
• Karl Ivanovich Weber
• Karlivka
• Karl IV of Hungary
• Karl I von Hessen-Kassel
• Karlići
• Karl Jacobi
• Karl Jaeger
• Karl Jaffary
• Karl Jager
• Karl Jakob Weber
• Karl Jarres
• Karl J. Brommeland
• Karl Jenkins: Requiem
• Karl Joel
• Karl Joel (philosopher)
• Karl Johan Andersson
• Karl Johan Astrom
• Karl Johan Edvardsen
• Karl Johan Fjermeros