Three ships in the United States Navy have been named USS Saco for the Saco River and for the Saco, Maine.

• The first {{USS|Saco|1863}} was a gunboat launched in 1863, served in the American Civil War and sold in 1883.
• The second {{USS|Saco|YT-31}} was a steam tugboat, built in 1912. She was acquired by the Navy in 1918 and served as a yard tug until 1927.
• The third {{USS|Saco|YTB-796}} was a yard tug launched into service in 1968 and struck from the Naval Vessel Register in 2005, after serving in Guam.

• Margaret Hudson Pemberton
• Margaret Hughes (disambiguation)
• Margaret Hunt Hill
• Margaret Hurley
• Margaret Hutchinson
• Margaret H. Woodward
• Margareth Zelle
• Margaret I, Countess of Hainaut
• Margaret I. Cuomo
• Margaret Ida Balfour
• Margaret I. Handy
• Margaret II, Countess of Hainault
• Margaret Illington
• Margaret Ingels
• Margaret I of Norway
• Margaret Irvine
• Margaret Irving
• Margaret Isabel Cole
• Margaret Isabel Dicksee
• Margaret Isabel Postgate
• Margaret Ismay
• Margaret Jackson (1917 - 2013)
• Margaret Jackson (climber)
• Margaret Jackson (disambiguation)
• Margaret Jackson (secretary)