| 词条 | 5α-Dihydroaldosterone |
| 释义 |
| ImageFile = 5α-Dihydroaldosterone.svg | ImageSize = | ImageAlt = | IUPACName = (5S,8S,9S,10S,11S,13R,14S,17S)-11-Hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-13-carbaldehyde | OtherNames = 11β,21-Dihydroxy-3,20-dioxo-5α-pregnan-18-al | Section1 = {{Chembox Identifiers | CASNo = 70952-53-3 | ChemSpiderID = 20087956 | InChI = 1S/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h11-12,14-17,19,22,25H,2-10H2,1H3/t12-,14-,15-,16+,17-,19+,20-,21+/m0/s1 | InChIKey = IIBOWSHDTFRYKU-WHIQTFJJSA-N | PubChem = 21151227 | SMILES = C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C=O)O | Section2 = {{Chembox Properties | C=21 | H=30 | O=5 | MolarMass = 362.466 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}5α-Dihydroaldosterone is a metabolite of aldosterone that is formed by 5α-reductase.[1] It is a potent antinatriuretic agent similarly to but somewhat different from aldosterone.[1] It is produced in the kidneys.[1] References1. ^1 2 {{cite journal | vauthors = Azzouni F, Godoy A, Li Y, Mohler J | title = The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases | journal = Adv Urol | volume = 2012 | issue = | pages = 530121 | date = 2012 | pmid = 22235201 | pmc = 3253436 | doi = 10.1155/2012/530121 | url = }} {{Endogenous steroids}}{{Mineralocorticoid receptor modulators}}{{DEFAULTSORT:Dihydroaldosterone, 5α-}}{{Steroid-stub}} 5 : Aldehydes|Diketones|Diols|Mineralocorticoids|Pregnanes |
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