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词条 Acetic acid (medical use)
释义

  1. Medical uses

  2. References

{{Infobox drug
| drug_name = Acetic acid
| INN =
| type =
| IUPAC_name =
| image = Acetic-acid-2D-flat.png
| alt =
| caption = Chemical formula of acetic acid
| synonyms = Vinegar
| pronounce = a-SEE-tik
| tradename = Acetasol, Vasotate, Acid Jelly, Domeboro Otic, others
| Drugs.com = {{Drugs.com|monograph|acetic-acid}}
| MedlinePlus =
| pregnancy_AU =
| pregnancy_AU_comment =
| pregnancy_US =
| pregnancy_category=
| routes_of_administration = ear drops
| legal_AU =
| legal_AU_comment =
| legal_CA =
| legal_DE =
| legal_NZ =
| legal_UK =
| legal_US = Rx-only
| legal_UN =
| legal_status =
| bioavailability =
| protein_bound =
| metabolism =
| metabolites =
| onset =
| elimination_half-life =
| duration_of_action =
| excretion =
| CAS_number = 64-19-7
| class =
| ATCvet =
| ATC_prefix = S02
| ATC_suffix = AA10
| PubChem = 176
| DrugBank = DB03166
| ChemSpiderID = 171
| chemical_formula = C2H4O2
| molecular_weight = 60.052
| smiles = CC(=O)O
| StdInChI = 1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
| StdInChIKey = QTBSBXVTEAMEQO-UHFFFAOYSA-N
}}Acetic acid, which at low concentrations is known as vinegar, is used as a medication to treat a number of conditions. As an eardrop it is used to treat infections of the ear canal.[1] It may be used with an ear wick.[2] As a liquid it is used to flush the bladder in those who have a urinary catheter in an attempt to prevent infection or blockage.[2] As a gel it may be used to adjust the pH of the vagina.[3] It may also be applied to the cervix to help detect cervical cancer during screening.[4]

Side effects may include burning at the site of application.[6] Allergic reactions may rarely occur.[5] Use is not recommended in the ear in people who have a hole in the eardrum.[8] It works against both bacterial and fungal causes of external ear infections.[6]

Acetic acid has been used medically since the time of Ancient Egypt.[7][8] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[9] Acetic acid is available as a generic medication.[2] In the United States a course of treatment with the ear preparation costs less than US$25.[10] Acetic acid is more commonly used for external ear infections in the developing world than the developed.[11]

Medical uses

Acetic acid may be applied to the cervix to help detect cervical cancer during screening in many areas in the developing world.[4] Acetic acid is applied to the cervix and if an area of white appears after about a minute the test is positive.[4]

References

1. ^{{cite web|title=Acetic acid (otic) medical facts from Drugs.com|url=https://www.drugs.com/mtm/acetic-acid-otic.html|website=www.drugs.com|accessdate=14 January 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170118041716/https://www.drugs.com/mtm/acetic-acid-otic.html|archivedate=18 January 2017|df=}}
2. ^{{cite web|title=Acetic Acid|url=https://www.drugs.com/monograph/acetic-acid.html|publisher=The American Society of Health-System Pharmacists|accessdate=8 January 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170118041827/https://www.drugs.com/monograph/acetic-acid.html|archivedate=18 January 2017|df=}}
3. ^{{cite web|title=Acetic acid gel: Indications, Side Effects, Warnings - Drugs.com|url=https://www.drugs.com/cdi/acetic-acid-gel.html|website=www.drugs.com|accessdate=14 January 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170118041818/https://www.drugs.com/cdi/acetic-acid-gel.html|archivedate=18 January 2017|df=}}
4. ^{{cite journal|last1=Fokom-Domgue|first1=J|last2=Combescure|first2=C|last3=Fokom-Defo|first3=V|last4=Tebeu|first4=PM|last5=Vassilakos|first5=P|last6=Kengne|first6=AP|last7=Petignat|first7=P|title=Performance of alternative strategies for primary cervical cancer screening in sub-Saharan Africa: systematic review and meta-analysis of diagnostic test accuracy studies.|journal=BMJ (Clinical research ed.)|date=3 July 2015|volume=351|pages=h3084|pmid=26142020|pmc=4490835}}
5. ^{{cite web|title=Acetic acid otic Side Effects in Detail - Drugs.com|url=https://www.drugs.com/sfx/acetic-acid-otic-side-effects.html|website=www.drugs.com|accessdate=14 January 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170118041810/https://www.drugs.com/sfx/acetic-acid-otic-side-effects.html|archivedate=18 January 2017|df=}}
6. ^{{cite web|title=Acetic Acid - FDA prescribing information, side effects and uses|url=https://www.drugs.com/pro/acetic-acid.html|website=www.drugs.com|accessdate=14 January 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170118041704/https://www.drugs.com/pro/acetic-acid.html|archivedate=18 January 2017|df=}}
7. ^{{cite book|last1=Cook|first1=Larry|title=The Beginner's Guide to Natural Living: How to Cultivate a More Natural Lifestyle to Lose Weight, Prevent Degenerative Disease, Improve Your Energy and Attain Vibrant Health|date=2005|publisher=EcoVision Communications|isbn=9780975536186|page=107|url=https://books.google.ca/books?id=9_h08MyyjVMC&pg=PA107|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20170116165823/https://books.google.ca/books?id=9_h08MyyjVMC&pg=PA107|archivedate=2017-01-16|df=}}
8. ^{{cite book|last1=Cumston|first1=C. G.|title=The History of Medicine|date=2013|publisher=Routledge|isbn=9781136194252|page=Chapter 2|url=https://books.google.ca/books?id=Obb7AQAAQBAJ&pg=PT69|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20170116165728/https://books.google.ca/books?id=Obb7AQAAQBAJ&pg=PT69|archivedate=2017-01-16|df=}}
9. ^{{cite web|title=WHO Model List of Essential Medicines (19th List)|url=http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|work=World Health Organization|accessdate=8 December 2016|date=April 2015|deadurl=no|archiveurl=https://web.archive.org/web/20161213052708/http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|archivedate=13 December 2016|df=}}
10. ^{{cite book|last1=Hamilton|first1=Richart|title=Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition|date=2015|publisher=Jones & Bartlett Learning|isbn=9781284057560|page=252}}
11. ^{{cite book|last1=Desai|first1=Bobby|last2=Desai|first2=Alpa|title=Primary Care for Emergency Physicians|date=2016|publisher=Springer|isbn=9783319443607|page=36|url=https://books.google.ca/books?id=1DOgDQAAQBAJ&pg=PA36|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20170116170120/https://books.google.ca/books?id=1DOgDQAAQBAJ&pg=PA36|archivedate=2017-01-16|df=}}
{{portal bar|Pharmacy and pharmacology|Medicine}}

2 : World Health Organization essential medicines|RTT

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