词条 | Actino-ugpB RNA motif |
释义 |
| Name = Actino-ugpB | image = RF02927.svg | width = | caption = Consensus secondary structure and sequence conservation of Actino-ugpB RNA | Symbol = Actino-ugpB | AltSymbols = | Rfam = RF02927 | miRBase = | miRBase_family = | RNA_type = Gene; sRNA | Tax_domain = | GO = | SO = {{SO|0001263}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }}{{DISPLAYTITLE:Actino-ugpB RNA motif}} The Actino-ugpB RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] Actino-ugpB motifs are found in strains of the species Gardnerella vaginalis, within the phylum Actinobacteria. It is ambiguous whether Actino-ugpB RNAs function as cis-regulatory elements or whether they operate in trans. Many of the RNAs are upstream of the gene 'ugpB', which encodes a protein putatively involved in sugar transport. However, several of the RNAs are not located upstream of a protein-coding gene. Structurally, the motif consists of two hairpins with conserved nucleotides located in the stems and outside of the hairpins, but not in their terminal loops. Reference1. ^{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811–10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 |url=}} {{bioinformatics-stub}} 2 : RNA|Bioinformatics |
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