“Adrian R. Krainer”的意思、由来-开放百科全书

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Adrian R. Krainer

释义

Early life and education
Career
References

{{short description|Uruguayan neuroscientist}}{{Use mdy dates|date=October 2018}}{{Use American English|date=October 2018}}Adrian R. Krainer is a Uruguayan-American Biochemist and Molecular Geneticist. Krainer holds the St. Giles Foundation Professorship at Cold Spring Harbor Laboratory. He is a 2019 Breakthrough Prize Laureate in Lifesciences for his contributions to the understanding of the RNA gene-splicing process and, in collaboration with fellow Prize Laureate Dr. Frank Bennet of Ionis Pharmaceuticals, the development of medical interventions that target the gene-splicing process, including Spinraza, which is the first treatment for the genetic disorder Spinal Muscular Atrophy.

Early life and education

Adrian R. Krainer was born in Montevideo, Uruguay to a Jewish family of Hungarian and Romanian descent. He has one older brother, who is a chemical engineer. His father did forced labor for two years in a Romanian labor camp (Ferma Alba) during World War II. After the war, his father's original surname, Kreiner changed to Krainer due to a clerical error when he was a refugee in Italy. His parents owned a small leather business in Montevideo. Krainer attended a private bilingual French-Spanish elementary school. He later attended a public school for two years before completing his pre-college education with four years at a private Spanish-Hebrew school. Krainer lived through political unrest during his teenage years, including urban guerrilla and military dictatorship. Krainer received a full scholarship from Columbia University and completed a Bachelor of Arts in Biochemistry in 1981. He graduated cum laude and Phi Beta Kappa. In 1986, he earned a Doctor of Philosophy in Biochemistry from Harvard University.^[1]

Career

From 1986-1989, Krainer conducted postdoctoral research as the first Cold Spring Harbor Fellow at the Cold Spring Harbor Laboratory. Krainer worked as an Assistant Professor from 1989-1990, Associate Professor from 1990-1994, and Professor since 1994. Krainer is a faculty member of the graduate programs in Genetics, Molecular and Cellular Biology, and Molecular Genetics and Microbiology at State University of New York, Stony Brook.^[1] Krainer holds the St. Giles Foundation Professorship at Cold Spring Harbor Laboratory.^[2]

References

1. ^¹{{Cite web|url=https://oh.sciencehistory.org/sites/default/files/krainer_ar_0582_suppl.pdf|title=ADRIAN R. KRAINER|last=Maestrejuan|first=Andrea R.|date=1997-09-09|website=Chemical Heritage Foundation|archive-url=|archive-date=|dead-url=|access-date=2018-10-16}}
2. ^{{Cite news|url=https://www.cshl.edu/research/faculty-staff/adrian-r-krainer/#research-profile|title=Adrian R. Krainer - Cold Spring Harbor Laboratory|work=Cold Spring Harbor Laboratory|access-date=2018-10-16|language=en-US}}

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