| 释义 |
- Function
- References
- Further reading
{{Infobox_gene}}Alcohol dehydrogenase, iron containing 1 is a protein that in humans is encoded by the ADHFE1 gene.[1] Function The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues.[2] References 1. ^{{cite web | title = Entrez Gene: Alcohol dehydrogenase, iron containing 1 | url = https://www.ncbi.nlm.nih.gov/gene/137872 | accessdate = 2017-06-16 }}
2. ^{{cite journal | vauthors = Kardon T, Noël G, Vertommen D, Schaftingen EV | title = Identification of the gene encoding hydroxyacid-oxoacid transhydrogenase, an enzyme that metabolizes 4-hydroxybutyrate | journal = FEBS Letters | volume = 580 | issue = 9 | pages = 2347–50 | date = April 2006 | pmid = 16616524 | doi = 10.1016/j.febslet.2006.02.082 }}
Further reading {{refbegin |33em}}- {{cite journal | vauthors = Deng Y, Wang Z, Gu S, Ji C, Ying K, Xie Y, Mao Y | title = Cloning and characterization of a novel human alcohol dehydrogenase gene (ADHFe1) | journal = DNA Sequence | volume = 13 | issue = 5 | pages = 301–6 | date = October 2002 | pmid = 12592711 | doi = 10.1080/1042517021000011636 }}
- {{cite journal | vauthors = Lyon RC, Johnston SM, Panopoulos A, Alzeer S, McGarvie G, Ellis EM | title = Enzymes involved in the metabolism of gamma-hydroxybutyrate in SH-SY5Y cells: identification of an iron-dependent alcohol dehydrogenase ADHFe1 | journal = Chemico-Biological Interactions | volume = 178 | issue = 1–3 | pages = 283–7 | date = March 2009 | pmid = 19013439 | doi = 10.1016/j.cbi.2008.10.025 }}
- {{cite journal | vauthors = Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ | title = Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression | journal = PLoS One | volume = 5 | issue = 9 | pages = e12862 | date = September 2010 | pmid = 20877624 | pmc = 2943476 | doi = 10.1371/journal.pone.0012862 | bibcode = 2010PLoSO...512862H }}
- {{cite journal | vauthors = Tae CH, Ryu KJ, Kim SH, Kim HC, Chun HK, Min BH, Chang DK, Rhee PL, Kim JJ, Rhee JC, Kim YH | title = Alcohol dehydrogenase, iron containing, 1 promoter hypermethylation associated with colorectal cancer differentiation | journal = BMC Cancer | volume = 13 | issue = | pages = 142 | date = March 2013 | pmid = 23517143 | pmc = 3618294 | doi = 10.1186/1471-2407-13-142 }}
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