VPL or Vpl may refer to:

• VPL (brand), an American fashion label
• Vancouver Public Library, public library system in Vancouver, British Columbia
• Vaughan Public Libraries, public library system in Vaughan, Ontario
• Ventral posterolateral nucleus, a part of the thalamus in the brain
• Victorian Premier League, the highest association football league in Victoria, Australia
• VPL Research, a company started by Jaron Lanier
• Viipuri Province, a former province of Finland
• Visible panty line, visible underwear beneath somebody's outer clothing
• Visibly pushdown language, a kind of formal language
• ViRC Programming Language, a programming interface for Visual IRC
• Visual programming language, a style of programming language
• Kodak Vericolor II, Type L film

• Casper Phair
• Casper (skateboarding)
• Casper slide
• Casper the friendly ghost
• Casper Van Dien
• Casper Weinberger
• Casper W. Weinberger
• Casper, WY
• Casper, Wyoming
• Casper Yost
• Casper–Natrona County International Airport
• Caspian
• Caspian Airline
• Caspian Airlines
• Caspian Flotilla
• Caspian gull
• Caspian, MI
• Caspian, Michigan
• Caspian oil pipeline
• Caspian plover
• Caspian sea
• Caspian seal
• Caspian seas
• Caspian snowcock
• Caspian tern