| 词条 | Artesunate/mefloquine |
| 释义 |
| drug_name = | type = combo | component1 = Artesunate | class1 = artemisinin | component2 = Mefloquine | class2 = antimalarial | pronounce = | tradename = | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_AU_comment = | legal_CA = | legal_UK = | legal_US = | legal_UN = | legal_NZ = | legal_status = | routes_of_administration = | CAS_number = | ATCvet = | ATC_prefix = P01 | ATC_suffix = BF02 | PubChem = | DrugBank = }}Artesunate/mefloquine is a medication used to treat malaria.[1] It is a fixed dose combination of artesunate and mefloquine.[1] Specifically it is recommended to treat uncomplicated falciparum malaria.[1] It is taken by mouth.[1] Side effects are similar to the medications being used separately.[1] Use is recommended as it decreases the possibility of either medications being used alone.[1] Dose forms appropriate for children are also available.[1] Artesunate/mefloquine came into commercial use in 2008.[2] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[3] It is approved for medical use in Brazil, India, and Malaysia.[1] In 2012 a course of treatment cost US$2.50.[2] It is not commercially available in the United States.[4] Medical usesArtesunate/mefloquine is a recommended treatment in Southeast Asia while in Africa artesunate/amodiaquine, artemether/lumefantrine, artesunate/sulfadoxine/pyrimethamine are often preferred.[5] See also
References1. ^1 2 3 4 {{cite book|last1=Organization|first1=World Health|title=The Selection and Use of Essential Medicines: Report of the WHO Expert Committee, 2013 (including the 18th WHO Model List of Essential Medicines and the 4th WHO Model List of Essential Medicines for Children).|date=2014|publisher=World Health Organization|isbn=9789241209854|page=43|url=https://books.google.ca/books?id=fa8XDAAAQBAJ&pg=PA43|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20161220163648/https://books.google.ca/books?id=fa8XDAAAQBAJ&pg=PA43|archivedate=2016-12-20|df=}} {{portal bar|Pharmacy and pharmacology|Medicine}}2. ^1 {{cite book|last1=Staines|first1=Henry M.|last2=Krishna|first2=Sanjeev|title=Treatment and Prevention of Malaria: Antimalarial Drug Chemistry, Action and Use|date=2012|publisher=Springer Science & Business Media|isbn=9783034604802|page=239|url=https://books.google.ca/books?id=IXWOXUpylO8C&pg=PA239|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20161220161905/https://books.google.ca/books?id=IXWOXUpylO8C&pg=PA239|archivedate=2016-12-20|df=}} 3. ^1 2 3 {{cite web|title=WHO Model List of Essential Medicines (19th List)|url=http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|work=World Health Organization|accessdate=8 December 2016|date=April 2015|deadurl=no|archiveurl=https://web.archive.org/web/20161213052708/http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|archivedate=13 December 2016|df=}} 4. ^{{cite book|last1=Sanford|first1=Christopher A.|last2=Jong|first2=Elaine C.|last3=Pottinger|first3=Paul S.|title=The Travel and Tropical Medicine Manual|date=2016|publisher=Elsevier Health Sciences|isbn=9780323417426|page=307|edition=5|url=https://books.google.ca/books?id=jyTRDAAAQBAJ&pg=PA307|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20161220162041/https://books.google.ca/books?id=jyTRDAAAQBAJ&pg=PA307|archivedate=2016-12-20|df=}} 5. ^{{cite book|last1=Marcondes|first1=Carlos Brisola|title=Arthropod Borne Diseases|date=2016|publisher=Springer|isbn=9783319138848|page=35|url=https://books.google.ca/books?id=Qs55DQAAQBAJ&pg=PA335|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20161220163853/https://books.google.ca/books?id=Qs55DQAAQBAJ&pg=PA335|archivedate=2016-12-20|df=}} 4 : Malaria|Combination drugs|World Health Organization essential medicines|RTT |
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