| 释义 |
- Function
- References
- Further reading
{{Infobox_gene}}Autophagy related 9B is a protein that in humans is encoded by the ATG9B gene.[1]FunctionThis gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the posttranscriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants. References 1. ^{{cite web| title = Entrez Gene: Autophagy related 9B| url = https://www.ncbi.nlm.nih.gov/gene/285973| accessdate = 2017-06-12}}
Further reading {{refbegin | 2}}- {{cite journal |vauthors=Yamada T, Carson AR, Caniggia I, Umebayashi K, Yoshimori T, Nakabayashi K, Scherer SW |title=Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast |journal=J. Biol. Chem. |volume=280 |issue=18 |pages=18283–90 |year=2005 |pmid=15755735 |doi=10.1074/jbc.M413957200 |url=}}
- {{cite journal |vauthors=Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS, Ahn CH, Yoo NJ, Lee SH |title=Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability |journal=J. Pathol. |volume=217 |issue=5 |pages=702–6 |year=2009 |pmid=19197948 |doi=10.1002/path.2509 |url=}}
- {{cite journal |vauthors=Han X, Zheng T, Lan Q, Zhang Y, Kilfoy BA, Qin Q, Rothman N, Zahm SH, Holford TR, Leaderer B, Zhang Y |title=Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma |journal=Cancer Epidemiol. Biomarkers Prev. |volume=18 |issue=5 |pages=1429–38 |year=2009 |pmid=19423521 |pmc=2965355 |doi=10.1158/1055-9965.EPI-09-0001 |url=}}
- {{cite journal |vauthors=Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ |title=Common variation in genes related to innate immunity and risk of adult glioma |journal=Cancer Epidemiol. Biomarkers Prev. |volume=18 |issue=5 |pages=1651–8 |year=2009 |pmid=19423540 |pmc=2771723 |doi=10.1158/1055-9965.EPI-08-1041 |url=}}
- {{cite journal |vauthors=Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD |title=Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip |journal=Am. J. Hum. Genet. |volume=85 |issue=5 |pages=628–42 |year=2009 |pmid=19913121 |pmc=2775832 |doi=10.1016/j.ajhg.2009.10.014 |url=}}
- {{cite journal |vauthors=McGeachie M, Ramoni RL, Mychaleckyj JC, Furie KL, Dreyfuss JM, Liu Y, Herrington D, Guo X, Lima JA, Post W, Rotter JI, Rich S, Sale M, Ramoni MF |title=Integrative predictive model of coronary artery calcification in atherosclerosis |journal=Circulation |volume=120 |issue=24 |pages=2448–54 |year=2009 |pmid=19948975 |pmc=2810344 |doi=10.1161/CIRCULATIONAHA.109.865501 |url=}}
- {{cite journal |vauthors=Webber JL, Tooze SA |title=New insights into the function of Atg9 |journal=FEBS Lett. |volume=584 |issue=7 |pages=1319–26 |year=2010 |pmid=20083107 |doi=10.1016/j.febslet.2010.01.020 |url=}}
- {{cite journal |vauthors=Rajaraman P, Brenner AV, Neta G, Pfeiffer R, Wang SS, Yeager M, Thomas G, Fine HA, Linet MS, Rothman N, Chanock SJ, Inskip PD |title=Risk of meningioma and common variation in genes related to innate immunity |journal=Cancer Epidemiol. Biomarkers Prev. |volume=19 |issue=5 |pages=1356–61 |year=2010 |pmid=20406964 |pmc=3169167 |doi=10.1158/1055-9965.EPI-09-1151 |url=}}
- {{cite journal |vauthors=Ban HJ, Heo JY, Oh KS, Park KJ |title=Identification of type 2 diabetes-associated combination of SNPs using support vector machine |journal=BMC Genet. |volume=11 |issue= |pages=26 |year=2010 |pmid=20416077 |pmc=2875201 |doi=10.1186/1471-2156-11-26 |url=}}
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