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词条 Auxiliary metabolic genes
释义

  1. References

Auxiliary metabolic genes (AMGs) are found in many bacteriophages but originated in bacterial cells.[1] AMGs modulate host cell metabolism during infection so that the phage can replicate more efficiently. For instance, bacteriophages that infect the abundant marine cyanobacteria Synechococcus and Prochlorococcus (cyanophages) carry AMGs that have been acquired from their immediate host as well as more distantly-related bacteria.[2] Cyanophage AMGs support a variety of functions including photosynthesis,[3] carbon metabolism,[4] nucleic acid synthesis and metabolism.[5]

References

1. ^{{Cite journal|last=Breitbart|first=Mya|last2=Thompson|first2=Luke|last3=Suttle|first3=Curtis|last4=Sullivan|first4=Matthew|date=2007|title=Exploring the Vast Diversity of Marine Viruses|journal=Oceanography|volume=20|issue=2|pages=135–139|doi=10.5670/oceanog.2007.58}}
2. ^{{Cite journal|last=Crummett|first=Lisa T.|last2=Puxty|first2=Richard J.|last3=Weihe|first3=Claudia|last4=Marston|first4=Marcia F.|last5=Martiny|first5=Jennifer B.H.|date=2016|title=The genomic content and context of auxiliary metabolic genes in marine cyanomyoviruses|journal=Virology|volume=499|pages=219–229|doi=10.1016/j.virol.2016.09.016}}
3. ^{{Cite journal|last=Mann|first=Nicholas H.|last2=Cook|first2=Annabel|last3=Millard|first3=Andrew|last4=Bailey|first4=Shaun|last5=Clokie|first5=Martha|date=2003-08-14|title=Marine ecosystems: bacterial photosynthesis genes in a virus|journal=Nature|volume=424|issue=6950|pages=741|doi=10.1038/424741a|issn=1476-4687|pmid=12917674}}
4. ^{{Cite journal|last=Thompson|first=Luke R.|last2=Zeng|first2=Qinglu|last3=Kelly|first3=Libusha|last4=Huang|first4=Katherine H.|last5=Singer|first5=Alexander U.|last6=Stubbe|first6=Joanne|last7=Chisholm|first7=Sallie W.|date=2011-09-27|title=Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=108|issue=39|pages=E757–764|doi=10.1073/pnas.1102164108|issn=1091-6490|pmc=3182688|pmid=21844365}}
5. ^{{Cite journal|last=Enav|first=Hagay|last2=Mandel-Gutfreund|first2=Yael|last3=Béjà|first3=Oded|date=2014-03-26|title=Comparative metagenomic analyses reveal viral-induced shifts of host metabolism towards nucleotide biosynthesis|journal=Microbiome|volume=2|issue=1|pages=9|doi=10.1186/2049-2618-2-9|issn=2049-2618|pmc=4022391|pmid=24666644}}
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3 : Genes|Bacteriophages|Metabolism

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