| 词条 | Avatrombopag |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = | IUPAC_name = 1-[3-Chloro-5-[[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1,3-thiazol-2-yl]carbamoyl]pyridin-2-yl]piperidine-4-carboxylic acid | image = Avatrombopag.svg | width = 200px | tradename = Doptelet | Drugs.com = | MedlinePlus = | licence_US = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | licence_EU = | INN_EMA = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | dependency_liability = | routes_of_administration = Oral | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 570406-98-3 | CAS_supplemental = | ATC_prefix = B02 | ATC_suffix = BX08 | ATC_supplemental = | PubChem = 9852519 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB11995 | KEGG = D10306 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 8028230 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 3H8GSZ4SQL | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 2103883 | C=29 | H=34 | Cl=2 | N=6 | O=3 | S=2 | smiles = C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C29H34Cl2N6O3S2/c30-20-15-23(41-17-20)24-27(37-12-10-35(11-13-37)21-4-2-1-3-5-21)42-29(33-24)34-26(38)19-14-22(31)25(32-16-19)36-8-6-18(7-9-36)28(39)40/h14-18,21H,1-13H2,(H,39,40)(H,33,34,38) | StdInChIKey_Ref = | StdInChIKey = OFZJKCQENFPZBH-UHFFFAOYSA-N }}Avatrombopag is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts) such as thrombocytopenia associated with chronic liver disease in adult patients who are to undergo a planned medical or dental procedure. It was approved by the Food and Drug Administration in May 21, 2018.[1] References1. ^[https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm608320.htm ]FDA approves new drug for patients with chronic liver disease who have low blood platelets and are undergoing a medical procedure {{Antihemorrhagics}}{{blood-drug-stub}} 7 : Drugs acting on the blood and blood forming organs|Orphan drugs|Thrombopoietin receptor agonists|Thiophenes|Chloropyridines|Thiazoles|Piperazines |
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