| 词条 | Benzylidene acetal |
| 释义 |
In organic chemistry, a benzylidene acetal is the functional group with the structural formula C6H5CH(OR)2 (R = alkyl, aryl). Benzylidene acetals are used as protecting groups in glycochemistry.[1][2] These compounds can also be oxidized to carboxylic acids in order to open important biological molecules, such as glycosaminoglycans, to other routes of synthesis.[3] They arise from the reaction of a 1,2- or 1,3-diols with benzaldehyde. Other aromatic aldehydes are also used.[4] References1. ^{{cite journal|author=David Crich|title=Mechanism of a Chemical Glycosylation Reaction|journal=Acc. Chem. Res.|year=2010|volume=43|issue=8|pages=1144–1153|doi=10.1021/ar100035r|pmid=20496888}} 2. ^{{cite journal|title=6-Bromo-6-deoxy Hexose Derivatives By Ring Opening Of Benzylidene Acetals With N-bromosuccinimide: Methyl 4-o-benzoyl-6-bromo-6-deoxy-α-d-glucopyranoside|author=S. Hanessian|journal=Org. Synth.|year=1987|volume=65|page= 243|doi=10.15227/orgsyn.065.0243}} 3. ^{{Cite journal|last=Banerjee|first=Amit|last2=Senthilkumar|first2=Soundararasu|last3=Baskaran|first3=Sundarababu|date=2015-12-07|title=Benzylidene Acetal Protecting Group as Carboxylic Acid Surrogate: Synthesis of Functionalized Uronic Acids and Sugar Amino Acids|journal=Chemistry - A European Journal|language=en|volume=22|issue=3|pages=902–906|doi=10.1002/chem.201503998|pmid=26572799|issn=0947-6539}} 4. ^{{cite journal|title=Protection Of Diols With 4-(Tert-butyldimethylsilyloxy)benzylidene Acetal And Its Deprotection|authors=Hiroyuki Osajima, Hideto Fujiwara, Kentaro Okano, Hidetoshi Tokuyama, Tohru Fukuyama|journal=Org. Synth.|year=2009|volume=86|page=130|doi=10.15227/orgsyn.086.0130}} 3 : Acetals|Functional groups|Protecting groups |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。