Bernacchi is a surname, and may refer to;

• Antonio Maria Bernacchi, Italian castrato singer (1685-1756)
• {{Interlanguage link multi|Clelia Bernacchi|it}}, Italian actress and dubber (1910-2006)
• Louis Bernacchi, physicist, astronomer and explorer (1876-1942)
• {{Interlanguage link multi|Piero Bernacchi|it}}, Italian journalist and presenter
• Quirico Bernacchi, Italian cyclist (1914-2006)

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