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词条 Bromofenofos
释义

  1. References

{{Infobox drug
| drug_name =
| INN =
| type =
| IUPAC_name = 3,3',5,5'-Tetrabromo-2'-hydroxy-2-biphenylyl dihydrogen phosphate
| image = Bromofenofos.svg
| width = 160
| caption =
| pronounce =
| tradename = Acedist
| Drugs.com =
| MedlinePlus =
| pregnancy_AU =
| pregnancy_AU_comment =
| pregnancy_US =
| pregnancy_category=
| routes_of_administration =
| legal_AU =
| legal_AU_comment =
| legal_BR =
| legal_BR_comment =
| legal_CA =
| legal_DE =
| legal_NZ =
| legal_UK =
| legal_US =
| legal_UN =
| legal_status =
| bioavailability =
| protein_bound =
| metabolism =
| metabolites =
| onset =
| elimination_half-life =
| duration_of_action =
| excretion =
| CAS_number = 21466-07-9
| class =
| ATCvet = yes
| ATC_prefix = P52
| ATC_suffix = AB02
| PubChem = 30652
| DrugBank =
| ChemSpiderID = 28444
| ChEMBL = 532998
| UNII = XTH861Q3CR
| ChEBI = 81726
| KEGG = C18392
| synonyms = Bromfenofos; Bromophenophos; Bromphenophos; Bromophenfos
| C=12|H=7|Br=4|O=5|P=1
| smiles = C1=C(C=C(C(=C1Br)O)C2=CC(=CC(=C2OP(=O)(O)O)Br)Br)Br
| StdInChI=1S/C12H7Br4O5P/c13-5-1-7(11(17)9(15)3-5)8-2-6(14)4-10(16)12(8)21-22(18,19)20/h1-4,17H,(H2,18,19,20)
| StdInChIKey=MMYHZEDBTMXYAF-UHFFFAOYSA-N
}}Bromofenofos is an anthelminthic agent used in veterinary medicine. It is used to treat common liver fluke (Fasciola hepatica) infections in cattle and sheep.[1][2]

It is teratogenic.[3][4]

References

1. ^{{Cite book | title = Saunders Comprehensive Veterinary Dictionary |author=Virginia P. Studdert |author2=Clive C. Gay |author3=Douglas C. Blood | publisher = Elsevier Health Sciences | date = 2011}}
2. ^{{Cite book | title = Veterinary Pharmacology and Toxicology |editor=Y. Ruckebusch |editor2=P.-L. Toutian |editor3=G.D. Koritz | publisher = Springer Science & Business Media | date = 2012 | page = 762}}
3. ^{{cite book | title = Catalog of Teratogenic Agents |author=Thomas H. Shepard |author2=Ronald J. Lemire | publisher = JHU Press | date = 2004 | pages = 52}}
4. ^{{cite journal | doi = 10.1007/BF01234673| title = Comparative embryolethal effect of bromofenofos and dephosphate bromofenofos in rats| journal = Archives of Toxicology| volume = 60| issue = 4| pages = 325–327| year = 1987| last1 = Yoshimura| first1 = Haruo}}
{{antiinfective-drug-stub}}

6 : Anthelmintics|Bromoarenes|Biphenyls|Organophosphates|Phenols|Veterinary drugs

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