词条 | Butirosin |
释义 |
| drug_name = | INN = Butirosin | type = | IUPAC_name = | image = Butirosin A structure.svg | image2 = Butirosin B structure.svg | alt = | caption = Butirosin A (top) and butirosin B (bottom) | pronounce = | tradename = | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_US = | pregnancy_category= | routes_of_administration = | legal_AU = | legal_AU_comment = | legal_BR = | legal_BR_comment = | legal_CA = | legal_DE = | legal_NZ = | legal_UK = | legal_US = | legal_UN = | legal_status = | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = | duration_of_action = | excretion = | CAS_number = | class = Aminoglycoside antibiotic | ATCvet = | ATC_prefix = | ATC_suffix = | PubChem = | ChEBI = 65109 | UNII = 8S52KR0L58 | SMILES = C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@@H](CCN)O)O)O[C@@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N | synonyms = Ambutyrosin; Butyrosin | chemical_formula = | molecular_weight = }}Butirosin is an antibiotic complex which is active against both Gram-positive and Gram-negative bacteria.[1] It is a mixture with butirosin A (80-85%) and butirocin B being the major components.[2] References1. ^{{cite journal | pmid = 4670492| pmc = 444273| year = 1972| last1 = Heifetz| first1 = C. L| title = Butirosin, a new aminoglycosidic antibiotic complex: Antibacterial activity in vitro and in mice| journal = Antimicrobial Agents and Chemotherapy| volume = 2| issue = 2| pages = 89–94| last2 = Fisher| first2 = M. W| last3 = Chodubski| first3 = J. A| last4 = Decarlo| first4 = M. O}} {{antiinfective-drug-stub}}2. ^{{cite book | title = The Dictionary of Drugs | author = J. Elks | publisher = Springer | date = 2014 | page = 198}} 1 : Aminoglycoside antibiotics |
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