| 释义 |
- Function
- References
- Further reading
{{Infobox_gene}}CD96 molecule is a protein that in humans is encoded by the CD96 gene. [1]FunctionThe protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]. References 1. ^{{cite web| title = Entrez Gene: CD96 molecule| url = https://www.ncbi.nlm.nih.gov/gene/10225| accessdate = 2018-07-03}}
Further reading {{refbegin | 2}}- {{cite journal |vauthors=Fuchs A, Cella M, Giurisato E, Shaw AS, Colonna M |title=Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155) |journal=J. Immunol. |volume=172 |issue=7 |pages=3994–8 |date=April 2004 |pmid=15034010 |doi= |url=}}
- {{cite journal |vauthors=Hosen N, Park CY, Tatsumi N, Oji Y, Sugiyama H, Gramatzki M, Krensky AM, Weissman IL |title=CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue=26 |pages=11008–13 |date=June 2007 |pmid=17576927 |pmc=1904175 |doi=10.1073/pnas.0704271104 |url=}}
- {{cite journal |vauthors=Kaname T, Yanagi K, Chinen Y, Makita Y, Okamoto N, Maehara H, Owan I, Kanaya F, Kubota Y, Oike Y, Yamamoto T, Kurosawa K, Fukushima Y, Bohring A, Opitz JM, Yoshiura K, Niikawa N, Naritomi K |title=Mutations in CD96, a member of the immunoglobulin superfamily, cause a form of the C (Opitz trigonocephaly) syndrome |journal=Am. J. Hum. Genet. |volume=81 |issue=4 |pages=835–41 |date=October 2007 |pmid=17847009 |pmc=2227933 |doi=10.1086/522014 |url=}}
- {{cite journal |vauthors=Meyer D, Seth S, Albrecht J, Maier MK, du Pasquier L, Ravens I, Dreyer L, Burger R, Gramatzki M, Schwinzer R, Kremmer E, Foerster R, Bernhardt G |title=CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains |journal=J. Biol. Chem. |volume=284 |issue=4 |pages=2235–44 |date=January 2009 |pmid=19056733 |doi=10.1074/jbc.M807698200 |url=}}
- {{cite journal |vauthors=Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M |title=New genetic associations detected in a host response study to hepatitis B vaccine |journal=Genes Immun. |volume=11 |issue=3 |pages=232–8 |date=April 2010 |pmid=20237496 |doi=10.1038/gene.2010.1 |url=}}
- {{cite journal |vauthors=Wu Y, Xiao M, Zhu L, Zhou XX, Gong Q, Xin X, Li CR, Zhou JF, Deng JN |title=[CD96 expression on bone marrow mononuclear cells in 91 patients with acute leukemia] |language=Chinese |journal=Zhongguo Shi Yan Xue Ye Xue Za Zhi |volume=19 |issue=3 |pages=585–8 |date=June 2011 |pmid=21729528 |doi= |url=}}
- {{cite journal |vauthors=Mohseni Nodehi S, Repp R, Kellner C, Bräutigam J, Staudinger M, Schub N, Peipp M, Gramatzki M, Humpe A |title=Enhanced ADCC activity of affinity maturated and Fc-engineered mini-antibodies directed against the AML stem cell antigen CD96 |journal=PLoS ONE |volume=7 |issue=8 |pages=e42426 |date=2012 |pmid=22879978 |pmc=3411760 |doi=10.1371/journal.pone.0042426 |url=}}
- {{cite journal |vauthors=Eriksson EM, Keh CE, Deeks SG, Martin JN, Hecht FM, Nixon DF |title=Differential expression of CD96 surface molecule represents CD8⁺ T cells with dissimilar effector function during HIV-1 infection |journal=PLoS ONE |volume=7 |issue=12 |pages=e51696 |date=2012 |pmid=23272144 |pmc=3521672 |doi=10.1371/journal.pone.0051696 |url=}}
- {{cite journal |vauthors=Chávez-González A, Dorantes-Acosta E, Moreno-Lorenzana D, Alvarado-Moreno A, Arriaga-Pizano L, Mayani H |title=Expression of CD90, CD96, CD117, and CD123 on different hematopoietic cell populations from pediatric patients with acute myeloid leukemia |journal=Arch. Med. Res. |volume=45 |issue=4 |pages=343–50 |date=May 2014 |pmid=24751333 |doi=10.1016/j.arcmed.2014.04.001 |url=}}
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