Charlotte Bruce may refer to:

• Charlotte Bruce (Prime Minister's wife) (1832–1906), wife of Henry Campbell-Bannerman
• Charlotte Bruce, wife of Terry L. Bruce
• Charlotte Bruce, wife of Frederick Locker-Lampson
• Charlotte Bruce (1771–1816), wife of Philip Charles Durham

• Cephalotes sucinus
• Cephalotes supercilii
• Cephalotes taino
• Cephalotes targionii
• Cephalotes texanus
• Cephalotes toltecus
• Cephalotes trichophorus
• Cephalotes umbraculatus
• Cephalotes unimaculatus
• Cephalotes ustus
• Cephalotes varians
• Cephalotes ventriosus
• Cephalotes vinosus
• Cephalotes wheeleri
• Cephalotos
• Cephalotribe
• Cephalotripsy
• Cephalotripsy (band)
• Cephalotropis
• Cephaloxys
• Cephaloziaceae
• Cephanasten
• Cephanodes
• Cephaoglycin acid
• Cepharanoline