| 词条 | Ciclometasone |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-Chloro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 4-(acetamidomethyl)cyclohexane-1-carboxylate | image = Cyclomethasone.svg | width = | tradename = Cycloderm, Telocort | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 67372-50-3 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 20055293 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 16736546 | UNII = | KEGG = | ChEBI = | ChEMBL = | C=32 | H=44 | Cl=1 | N=1 | O=7 | molecular_weight = 590.154 g/mol | SMILES = C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C5CCC(CC5)CNC(=O)C)O)C)O)Cl)C | StdInChI_Ref = | StdInChI = 1S/C32H44ClNO7/c1-18-13-25-24-10-9-22-14-23(36)11-12-29(22,3)31(24,33)26(37)15-30(25,4)32(18,40)27(38)17-41-28(39)21-7-5-20(6-8-21)16-34-19(2)35/h11-12,14,18,20-21,24-26,37,40H,5-10,13,15-17H2,1-4H3,(H,34,35)/t18-,20?,21?,24-,25-,26-,29-,30-,31-,32-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = UYVYDRXVNVNQEA-BJTOFBPUSA-N | synonyms = Cyclomethasone; RIB-222; 9α-Chloro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-[4-[(acetylamino)methyl]cyclo- hexyl]carboxylate; 21-[[[4-[(Acetylamino)methyl]cyclo- hexyl]carbonyl]oxy]-9α-chloro-11β,17α-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione }}Ciclometasone (brand names Cycloderm, Telocort) is a synthetic glucocorticoid corticosteroid which is marketed in Italy.[1][2] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA332|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=332–}} {{Glucocorticoids and antiglucocorticoids}}{{Glucocorticoid receptor modulators}}{{steroid-stub}}2. ^{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA230|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=230–}} 8 : Amines|Carboxylic acids|Chloroarenes|Corticosteroid esters|Diketones|Glucocorticoids|Pregnanes|Triols |
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