词条 | Cicortonide |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-2-(2-Chloroethoxy)-12-cyano-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,9a,10,10a,10b,11-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl acetate | image = Cicortonide.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 19705-61-4 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 20055442 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = | UNII = UL947A614K | KEGG = | ChEBI = | ChEMBL = 2104139 | C=29 | H=37 | Cl=1 | F=1 | N=1 | O=7 | SMILES = CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CC(=C5[C@@]4(CCC(=C5)OCCCl)C)C#N)F)O)C)OC(O2)(C)C | StdInChI_Ref = | StdInChI = 1S/C29H37ClFNO7/c1-16(33)37-15-23(35)29-24(38-25(2,3)39-29)12-20-21-10-17(14-32)19-11-18(36-9-8-30)6-7-26(19,4)28(21,31)22(34)13-27(20,29)5/h11,20-22,24,34H,6-10,12-13,15H2,1-5H3/t20-,21-,22-,24+,26-,27-,28-,29+/m0/s1 | StdInChIKey_Ref = | StdInChIKey = SOESEFMFRCCMQV-QWAPGEGQSA-N | synonyms = 21-(Acetyloxy)-3-(2-chloroethoxy)-9α-fluoro-11β-hydroxy-16α,17α-[(1-methylethylidene)bis(oxy)]-20-oxopregna-3,5-diene-6-carbonitrile; 3-(2-Chloroethoxy)-9α-fluoro-11β,16α,17α,21-tetrahydroxy-20-oxopregna-3,5-diene-6-carbonitrile cyclic 16,17-acetal with acetone 21-acetate }}Cicortonide is a synthetic glucocorticoid corticosteroid which was never marketed.[1] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA273|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=273–}} {{Glucocorticoid receptor modulators}}{{steroid-stub}} 10 : Acetate esters|Acetonides|Alcohols|Corticosteroid cyclic ketals|Diketones|Fluoroarenes|Glucocorticoids|Nitriles|Organochlorides|Pregnanes |
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