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词条 Cismadinone
释义

  1. References

{{Distinguish|Chlormadinone acetate}}{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (1S,2R,8S,10R,11S,14R,15S)-14-acetyl-8-chloro-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one
| image = Cismadinone.svg
| width =
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref =
| CAS_number = 54063-31-9
| CAS_supplemental =
| ATC_prefix =
| ATC_suffix =
| PubChem = 193990
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID_Ref =
| ChemSpiderID = 168332
| UNII = O00XM1O6TV
| C=21 | H=27 | Cl=1 | O=3
| molecular_weight = 362.89028 g/mol
| smiles = CC(=O)C1(CCC2C1(CCC3C2CC(C4=CC(=O)C=CC34C)Cl)C)O
| StdInChI_Ref =
| StdInChI = 1S/C21H27ClO3/c1-12(23)21(25)9-6-16-14-11-18(22)17-10-13(24)4-7-19(17,2)15(14)5-8-20(16,21)3/h4,7,10,14-16,18,25H,5-6,8-9,11H2,1-3H3/t14-,15+,16+,18+,19-,20+,21+/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = RNSISAJHBSCDGC-SCUQKFFVSA-N
| synonyms = 6α-Chloro-1,2-didehydro-17α-hydroxyprogesterone
}}Cismadinone (INN), also known as 6α-chloro-17α-hydroxypregna-1,4-diene-3,20-dione or 6α-chloro-δ1-dehydro-17α-hydroxyprogesterone, is a steroidal progestin closely related to the 17α-hydroxyprogesterone derivatives that was never marketed.[1][2] An acetylated form, cismadinone acetate, also exists, but similarly to cismadinone, was never marketed.[1]

References

1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA73|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=284}}
2. ^{{citation | author = World Health Organization | title = The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances | year = 2013 | page = 104 | url = http://apps.who.int/medicinedocs/collect/medicinedocs/pdf/s4895e/s4895e.pdf}}
{{Progesterone receptor modulators}}{{genito-urinary-drug-stub}}{{steroid-stub}}

4 : Organochlorides|Pregnanes|Progestogens|Abandoned drugs

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